isosorbide dinitrate


isosorbide dinitrate
A coronary vasodilator that acts via the formation of nitric oxide.

* * *

iso·sor·bide di·ni·trate -dī-'nī-.trāt n a coronary vasodilator C6H8N2O8 used esp. in the treatment of angina pectoris see ISORDIL

* * *

a drug used for the treatment of angina; it acts by relaxing the smooth muscle of both arteries and veins, thus causing dilatation (see vasodilator). It is administered by mouth (as tablets that are swallowed or dissolve under the tongue), as a spray (under the tongue or on the skin) or by injection; side-effects include headache, flushing, dizziness, and hypotension. Trade names: Angitak, Cedocard, Isocard, Isoket, <.
Isosorbide dinitrate is converted in the body to the active form of the drug, isosorbide mononitrate, which is also available as a treatment for angina. Trade names: Elantan, Imdur, Isodur, Isotard, Monit, etc.

* * *

[USP] the dinitric acid ester of isosorbide, having coronary and peripheral vasodilating properties; used in the treatment of coronary insufficiency and angina pectoris, administered sublingually and orally.

Medical dictionary. 2011.

Look at other dictionaries:

  • Isosorbide dinitrate — Systematic (IUPAC) name 1,4:3,6 dianhydro 2,5 di O nitro D glucitol Clinical data AHFS/ …   Wikipedia

  • isosorbide dinitrate — a drug used for the prevention and treatment of angina; it acts by relaxing the smooth muscle of both arteries and veins, thus causing dilatation (see vasodilator). It is administered by mouth (as tablets that are swallowed or dissolve under the… …   The new mediacal dictionary

  • isosorbide dinitrate — /uy seuh sawr buyd duy nuy trayt, sohr /, Pharm. a coronary vasodilator, C6H8N2O8, used in the prophylaxis and treatment of angina. [ISO + SORB(ITOL) + IDE; DI 1 + NITRATE] * * * …   Universalium

  • isosorbide dinitrate — /uy seuh sawr buyd duy nuy trayt, sohr /, Pharm. a coronary vasodilator, C6H8N2O8, used in the prophylaxis and treatment of angina. [ISO + SORB(ITOL) + IDE; DI 1 + NITRATE] …   Useful english dictionary

  • Isosorbide dinitrate/hydralazine — is a fixed dose combination drug treatment specifically indicated for black people with congestive heart failure. It is a combination of hydralazine (an antihypertensive) and isosorbide dinitrate (a vasodilator). It is the first race based… …   Wikipedia

  • Динитрат Изосорбида (Isosorbide Dinitrate) — лекарственное вещество, применяемое для лечения стенокардии у пациентов, плохо переносящих тринитрат глицерила. Расслабляет гладкую мускулатуру артерий и вен, вызывая их расширение. Назначается внутрь; побочные эффекты наблюдаются редко, но могут …   Медицинские термины

  • Isosorbide mononitrate — Systematic (IUPAC) name 8 nitrooxy 2,6 dioxabicyclo[3.3.0]octan 4 ol Clinical data AHFS/Drugs.com …   Wikipedia

  • Isosorbide — may refer to either of two medications used to treat angina pectoris: isosorbide dinitrate or isosorbide mononitrate.It may also refer to other isosorbide based medicines used as osmotic diuretics.Lowers portal pressure by vasodilation and… …   Wikipedia

  • dinitrate — see ISOSORBIDE DINITRATE * * * di·ni·trate (di niґtrāt) a compound of a base or a metal with two nitrate groups, as in lead dinitrate, Pb(NO3)2 …   Medical dictionary

  • isosorbide — A compound with diuretic properties prepared by acid dehydration of d glucitol. * * * iso·sor·bide .ī sō sȯr .bīd n 1) a diuretic C6H10O4 2) ISOSORBIDE DINITRATE * * * iso·sor·bide (i″so sorґbīd) [USP] a bicyclic ether derivative of… …   Medical dictionary