F (coefficient of inbreeding)

F (coefficient of inbreeding)
F is the symbol for the coefficient of inbreeding, a way of gauging how close two people are genetically to one another. The coefficient of inbreeding, F, is the probability that a person with two identical genes received both genes from one ancestor. Take, for example, the mating of first cousins who, by definition, share a set of grandparents. For any particular gene in the male, the chance that his female first cousin inherited the same gene from the same source is 1/8. Further, for any gene the man passes to his child, the chance is 1/8 that the woman has the same gene and ˝ that she transmits that gene to the child so 1/8 X ˝ = 1/16. Thus, a first-cousin marriage has a coefficient of inbreeding F =1/16. The added risks for the offspring of first cousins depend not only upon the coefficient of inbreeding but also upon the genetic family history and test results. For example, first cousins of Italian descent are at increased risk of carrying a gene for beta thalassemia and genetic laboratory tests may confirm that they are both beta-thalassemia gene carriers. There are always added risks in the mating of closely related persons and those risks are not entirely negligible.

Medical dictionary. 2011.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • coefficient of inbreeding — coefficient of inbreeding. См. коэффициент инбридинга. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Coefficient of inbreeding — A measure of how close two people are genetically to each another. The coefficient of inbreeding, symbolized by the letter F, is the probability that a person with two identical genes received both genes from one ancestor. Take a first cousin… …   Medical dictionary

  • coefficient of inbreeding — or coefficient of relation : a measure of the degree of inbreeding of an individual expressed as the percentage homozygous in that individual of characters heterozygous in the general population of its kind …   Useful english dictionary

  • coefficient of inbreeding — (F)    The proportion of homozygous loci in an individual; or, the probability that both alleles at corresponding loci were inherited from the same ancestor …   Forensic science glossary

  • inbreeding coefficient — n COEFFICIENT OF INBREEDING …   Medical dictionary

  • coefficient of relation — see coefficient of inbreeding …   Useful english dictionary

  • Coefficient of relationship — In population genetics, Sewall Wright s coefficient of relationship or coefficient of relatedness or relatedness or r is defined as 2 times the Coefficient of Inbreeding.[1] The Coefficient of Relatedness (or: coefficient of kinship) is defined… …   Wikipedia

  • Inbreeding — is breeding between close relatives, whether plant or animal. If practiced repeatedly, it leads to an increase in homozygosity of a population. A higher frequency of recessive, deleterious traits in homozygous form in a population can, over time …   Wikipedia

  • coefficient — 1. The expression of the amount or degree of any quality possessed by a substance, or of the degree of physical or chemical change normally occurring in that substance under stated conditions. 2. The ratio or factor that relates a quantity… …   Medical dictionary

  • inbreeding coefficient — įvaisos koeficientas statusas T sritis augalininkystė apibrėžtis Rodiklis, rodantis homozigotiškumo laipsnio padidėjimą populiacijoje dėl giminiško kryžminimo, lyginant su pirmine būsena. atitikmenys: angl. inbreeding coefficient rus. коэффициент …   Žemės ūkio augalų selekcijos ir sėklininkystės terminų žodynas

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”