lactoylglutathione lyase


lactoylglutathione lyase
Glyoxalase I; a lyase cleaving S-d-lactoylglutathione to glutathione and methylglyoxal. SYN: aldoketomutase, ketone-aldehyde mutase, methylglyoxalase.

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lac·to·yl·glu·ta·thi·one ly·ase (lak″to-əl-gloo″tə-thiґōn liґās) [EC 4.4.1.5] an enzyme of the lyase class that catalyzes the condensation of methylglyoxal and glutathione to form lactoylglutathione as a step in the conversion of methylglyoxal to lactic acid. See also glyoxalase.

Medical dictionary. 2011.

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  • Lactoylglutathione lyase — Identifiers EC number 4.4.1.5 CAS number 9033 12 9 …   Wikipedia

  • lactoylglutathione lyase — noun A glyoxalase enzyme that catalyzes the isomerization of hemithioacetal adducts …   Wiktionary

  • List of EC numbers (EC 4) — This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 4.1: Carbon Carbon LyasesEC… …   Wikipedia

  • glyoxalase — An enzyme, lactoylglutathione lyase (g. I) or hydroxyacylglutathione hydrolase (g. II), in red cells and other tissues that converts glyoxal and substituted glyoxals bound to glutathione into the corresponding free hydroxy acid s (g. II) or… …   Medical dictionary

  • methylglyoxalase — SYN: lactoylglutathione lyase. * * * meth·yl·gly·ox·a·lase (meth″əl gli okґsə lās) lactoylglutathione lyase …   Medical dictionary

  • hydroxyacylglutathione hydrolase — An enzyme with catalytic activity similar to that of lactoylglutathione lyase, but more general; catalyzes the hydrolysis of an S 2 hydroxyacylglutathione, producing glutathione and a 2 hydroxy acid anion. SEE ALSO: glyoxalase. * * *… …   Medical dictionary

  • GLO1 — Glyoxalase I, also known as GLO1, is a human gene.cite web | title = Entrez Gene: GLO1 glyoxalase I| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2739| accessdate = ] It is a Lactoylglutathione lyase. PBB …   Wikipedia

  • aldoketomutase — SYN: lactoylglutathione lyase …   Medical dictionary

  • ketone-aldehyde mutase — SYN: lactoylglutathione lyase …   Medical dictionary