leucine


leucine
2-Amino-4-methylvaleric acid; the l-isomer is one of the amino acid s found in proteins; a nutritionally essential amino acid.
- l. aminopeptidase aminopeptidase (cytosol).
- l. dehydrogenase an enzyme that catalyzes the reaction of l-l., water, and NAD+ to produce NADH, ammonia, and 4-methyl-2-oxopentanoate; used in the treatment of certain tumors.
- l. zipper a structural motif found in a number of proteins ( e.g., some of the DNA-binding regulatory proteins) in which leucyl residues align along one edge of the helix and can interdigitate with a similar structure on another protein molecule. [Zipper, orig. a trademark for a fastening device with two rows of interlocking teeth]

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leu·cine 'lü-.sēn n a white crystalline essential amino acid C6H13NO2 obtained by the hydrolysis of most dietary proteins abbr. Leu

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n.

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leu·cine (Leu) (L) (looґsēn) [Gr. leukos white] an essential amino acid, 2-amino-4-methylpentanoic acid, necessary for optimal growth in infants and for nitrogen equilibrium in human adults. It is obtained by the digestion or hydrolytic cleavage of protein. See also table at amino acid. [USP] a preparation of leucine used as a dietary supplement.

Medical dictionary. 2011.

Look at other dictionaries:

  • Leucine — L ou S(+) leucine D ou R( ) leucine Général …   Wikipédia en Français

  • leucine — [ løsin ] n. f. • 1832; de leuc(o) et ine ♦ Biochim. Acide aminé essentiel, l un des vingt constituants des protéines. ⇒ isoleucine. ● leucine nom féminin Aminoacide dont l antipode lévogyre, la L leucine, est un constituant essentiel des… …   Encyclopédie Universelle

  • Leucine — Leu cine (l[=oo] s[=e]n), Leucin Leu cin(l[=u] s[i^]n), n. [Gr. leyko s white.] (Physiol. Chem.) a naturally occurring alpha amino acid ({(CH3)2CH.CH2.CH(NH2) COOH}), one of the building units of almost all proteins of living organisms, both… …   The Collaborative International Dictionary of English

  • leucine — [lo͞o′sēn΄, lo͞o′sin] n. [< Gr leukos, white (see LIGHT1) + INE3] an essential amino acid, (CH3) 2CHCH2CH(NH2)COOH, produced by the hydrolysis of proteins by pancreatic enzymes during digestion and by the putrefaction of nitrogenous organic… …   English World dictionary

  • Leucine — NatOrganicBox name= ( S ) 2 amino 4 methyl pentanoic acid PubChem=6106 CAS=61 90 5 SMILES=CC(C)C [C@H] (N)C(O)=O C=6 |H=13 |N=1 |O=2 mass=131.18 g/molLeucine (abbreviated as Leu or L) [cite web | author=IUPAC IUBMB Joint Commission on Biochemical …   Wikipedia

  • Leucine — Als Leucine fasst man zunächst die vier isomeren Aminosäuren Leucin, Isoleucin, tert Leucin und Norleucin zusammen. Im Vergleich mit den vier Butanolen kann man sie als butylsubstituierte Glycine auffassen; damit sind alle vier Varianten… …   Deutsch Wikipedia

  • leucine — leucinas statusas T sritis chemija formulė (CH₃)₂CHCH₂CH(NH₂)COOH santrumpa( os) Leu, L atitikmenys: angl. leucine rus. лейцин ryšiai: sinonimas – 2 amino 4 metilpentano rūgštis …   Chemijos terminų aiškinamasis žodynas

  • leucine — noun Etymology: French, from leuc leuk Date: 1826 a white crystalline essential amino acid C6H13NO2 obtained by the hydrolysis of most dietary proteins …   New Collegiate Dictionary

  • leucine — n. [Gr. leukos, white] An amino acid, x amino isocaproic acid found in tissues of various invertebrates …   Dictionary of invertebrate zoology

  • leucine — (= leu; L; 2 amino 4 methylpentanoic acid; 131 D) The most abundant amino acid found in proteins. Confers hydrophobicity and has a structural rather than a chemical role …   Dictionary of molecular biology


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