ligation


ligation
1. Application of a ligature. 2. The act of binding or annealing. [L. ligatio, fr. ligo, to bind]
- blunt-end l. a reaction that joins two DNA duplexes directly at their blunt ends.
- enzyme-catalyzed l. an enzyme-mediated joining of phosphodiester linkage of two stretches of DNA or RNA, or of peptide linkage of two polypeptides.
- pole l. a l. at the root of an organ to shut off or diminish blood supply.
- surgical l. in dentistry, the surgical exposure of an unerupted tooth so that a metal ligature can be placed around its cervix and fastened to an orthodontic appliance to facilitate eruption.
- tooth l. the binding together of teeth with wire for stabilization and immobilization following traumatic injury or orthognathic surgery, or during periodontal therapy.
- tubal l. interruption of the continuity of the oviducts by cutting, cautery, or by a plastic or metal device to prevent future conception.

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li·ga·tion lī-'gā-shən n
1 a) the surgical process of tying up an anatomical channel (as a blood vessel)
b) the process of joining together chemical chains (as of DNA or protein)
2) something that binds: LIGATURE

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n.
the application of a ligature.

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li·ga·tion (li-gaґshən) [L. ligatio] 1. the application of a ligature. 2. the process of annealing or joining, such as the DNA ligase–catalyzed joining of two DNA fragments to form a recombinant molecule.

Medical dictionary. 2011.

Look at other dictionaries:

  • Ligation — bei Fremd DNA Einbau in Plasmid Unter Ligation versteht man in der Molekularbiologie die enzymkatalysierte Verknüpfung zweier DNA oder RNA Segmente an ihren Enden. Dabei wird das 3 Hydroxy Ende mit dem 5 Phosphat Ende der Nukleinsäurensegmente… …   Deutsch Wikipedia

  • Ligation — may refer to:* The act of making a ligature (tie). In medicine, a ligature is a device, similar to a tourniquet, usually of thread or string, tied around a limb, blood vessel or similar to restrict blood flow. A ligature can be used for tumor… …   Wikipedia

  • Ligation — Li*ga tion (l[ i]*g[=a] sh[u^]n), n. [L. ligatio, fr. ligare to bind. Cf. {Liaison}.] 1. The act of binding, or the state of being bound. [1913 Webster] 2. That which binds; bond; connection. [1913 Webster] Tied with tape, and sealed at each fold …   The Collaborative International Dictionary of English

  • ligation — 1590s, from M.Fr. ligation, from L.L. ligationem (nom. ligatio), noun of action from pp. stem of ligare to bind (see LIGAMENT (Cf. ligament)) …   Etymology dictionary

  • ligation — ligation. См. лигирование. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • ligation — index attachment (act of affixing) Burton s Legal Thesaurus. William C. Burton. 2006 …   Law dictionary

  • ligation — ligative /lig euh tiv/, adj. /luy gay sheuhn/, n. 1. the act of ligating, esp. of surgically tying up a bleeding artery. 2. anything that binds or ties up; ligature. [1590 1600; < LL ligation (s. of ligatio), equiv. to L ligat(us) (see LIGATE) +… …   Universalium

  • ligation — /laɪˈgeɪʃən/ (say luy gayshuhn) noun → tubal ligation …   Australian English dictionary

  • ligation — noun (surgery) tying a duct or blood vessel with a ligature (as to prevent bleeding during surgery) • Derivationally related forms: ↑ligate • Topics: ↑surgery • Hypernyms: ↑tying, ↑ligature …   Useful english dictionary

  • ligation — noun Date: 1597 1. an act of ligating 2. something that binds ; ligature …   New Collegiate Dictionary

  • ligation — noun a) Something that ties, a ligature. b) The act of tying, of applying a ligature …   Wiktionary


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