lipopolysaccharide


lipopolysaccharide
1. A compound or complex of lipid and carbohydrate. 2. The l. (endotoxin) released from the cell walls of Gram-negative organisms that produces septic shock.

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li·po·poly·sac·cha·ride .lip-ō-.päl-i-'sak-ə-.rīd, .lī-pō- n a large molecule consisting of lipids and sugars joined by chemical bonds abbr. LPS

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n.
a complex molecule containing both a lipid component and a polysaccharide component. Lipopolysaccharides are constituents of the cell walls of Gram-negative bacteria and are important in determining the antigenic properties of these bacteria.

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lipo·poly·sac·cha·ride (lip″o-pol″e-sakґə-rīd) 1. a complex of lipid and polysaccharide. 2. a major component of the cell wall of gram-negative bacteria, a type of endotoxin and important group-specific antigen (O antigen). The lipopolysaccharide molecule consists of three parts: lipid A, a glycolipid responsible for the endotoxic activity, which is covalently linked to a heteropolysaccharide chain; the first part of the chain is the core polysaccharide, which is constant within related strains; and the second part of the chain is the O-specific chain, which is highly variable. Lipopolysaccharide from Escherichia coli is a commonly used B-cell mitogen (polyclonal activator) in laboratory immunology. Abbreviated LPS.

Medical dictionary. 2011.

Look at other dictionaries:

  • Lipopolysaccharide — (LPS) sind relativ thermostabile (wärmeunempfindliche) Verbindungen aus fettähnlichen (Lipo ) Bestandteilen und Zucker Bestandteilen (Polysacchariden). Sie sind in der Äußeren Membran gramnegativer Bakterien enthalten. Sie wirken als Antigene und …   Deutsch Wikipedia

  • Lipopolysaccharide —   [ zaxa ], aus Lipiden und Polysacchariden bestehende charakteristische Bestandteile der äußeren Zellmembran gramnegativer Bakterien …   Universal-Lexikon

  • lipopolysaccharide — [lip΄ō pä΄lē sak′ə rīd΄, lī΄pōlē sak′ə rīd΄] n. Biochem. a large molecule that contains a polysaccharide and a lipid, found especially in cell membranes …   English World dictionary

  • Lipopolysaccharide — Structure of a lipopolysaccharide Lipopolysaccharides (LPS), also known as lipoglycans, are large molecules consisting of a lipid and a polysaccharide joined by a covalent bond; they are found in the outer membrane of Gram negative bacteria, act… …   Wikipedia

  • Lipopolysaccharide — Le lipopolysaccharide (LPS) est un composant essentiel (il n existe pas de mutant sans LPS) de la paroi bactérienne des bactéries à Gram négatif : c est une endotoxine. La structure est la suivante : L Ag O est spécifique d une espèce à …   Wikipédia en Français

  • lipopolysaccharide — noun Date: 1950 a large molecule consisting of lipids and sugars joined by chemical bonds …   New Collegiate Dictionary

  • lipopolysaccharide — n. [Gr. lipos, fat; polys, many; sakcharon, sugar] Molecule with a lipid attached to a polysaccharide …   Dictionary of invertebrate zoology

  • lipopolysaccharide — (lip o pol e sak ah raīd) A molecule containing both lipid and polysaccharide, which is important in the outer membrane of the gram negative cell wall …   Dictionary of microbiology

  • lipopolysaccharide — The major constituents of the cell walls of Gram negative bacteria. Highly immunogenic and stimulates the production of endogenous pyrogen interleukin 1 and tumour necrosis factor (TNF) …   Dictionary of molecular biology

  • lipopolysaccharide — /luyp oh pol ee sak euh ruyd , rid, luy poh /, n. Biochem. any of a class of polysaccharides to which lipids are attached. [1950 55; LIPO 1 + POLYSACCHARIDE] * * * …   Universalium


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