A class of enzymes that catalyzes the oxidation of unsaturated fatty acid s with O2 to yield hydroperoxides of the fatty acid s; 5-l. catalyzes the first step in leukotriene biosynthesis, acting on arachidonate. SYN: carotene oxidase, lipoxidase.

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li·pox·y·gen·ase li-'päk-sə-jə-.nās, lī-, -.nāz n a crystallizable enzyme that catalyzes the oxidation primarily of unsaturated fatty acids or unsaturated fats by oxygen and secondarily of carotenoids to colorless substances and that occurs esp. in soybeans and cereals

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li·poxy·ge·nase (lĭ-pokґsĭ-jən-ās) [EC] an enzyme of the oxidoreductase class that catalyzes the oxidation of linoleate and related polyunsaturated fatty acids to their hydroperoxide forms. Called also lipoxidase.

Medical dictionary. 2011.

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  • Lipoxygenase — Pfam box Symbol = Lipoxygenase Name = width =220 caption = Arachidonate 15 Lipoxygenase Pfam= PF00305 InterPro= IPR013819 SMART= PROSITE = PDOC00077 SCOP = 2sbl TCDB = OPM family= 87 OPM protein= 1zq4 PDB=PDB3|1y4kA:155 823 PDB3|2sblB:155 823… …   Wikipedia

  • Lipoxygenase — Lipoxygenasen sind Enzyme, die mehrfach ungesättigte Fettsäuren mit zwei Sauerstoffatomen oxidieren. Sie gehören somit zur Gruppe der Dioxygenasen. Die momentan bekannten sechs grundlegend verschiedenen Lipoxygenasen spielen eine Rolle im… …   Deutsch Wikipedia

  • Lipoxygénase — La lipoxygénase est un type de protéine enzymatique qui catalyse l oxydation des acides gras ou autres alcènes. Il en existe de multiples sortes. Elle entre notamment en jeu dans le métabolisme de l arachidonate (acide eicosatétraénoïque) pour sa …   Wikipédia en Français

  • lipoxygenase — (= 5 lipoxygenase; 5 LO) Enzyme that catalyses the addition of a hydroperoxy group to the 5 position of arachidonic acid, the first step in leukotriene synthesis …   Dictionary of molecular biology

  • lipoxygenase — noun Any of a class of enzymes that catalyse the oxidation of polyunsaturated fatty acids …   Wiktionary

  • Lipoxygenase — Lip|o|xy|ge|na|se [↑ Lip u. ↑ Oxygenase] Sammelbez. für Nichthäm Eisen Proteine, die als Oxidoreduktasen O2 auf Lipide u. ungesättigte Fettsäuren übertragen; beispielsweise entstehen aus Arachidonsäure auf diese Weise die Leukotriene u. Lipoxine …   Universal-Lexikon

  • lipoxygenase — li·pox·y·gen·ase …   English syllables

  • lipoxygenase — ¦lipˈäksə̇jəˌnās, ¦līp , ˌnāz noun ( s) Etymology: lip + oxygen + ase : lipoxidase …   Useful english dictionary

  • Lipoxygenase inhibitor — A Lipoxygenase inhibitor is a drug which slows down or stops the action of the lipoxygenase enzyme. More precisely, the term is almost always used to describe an inhibitor of the arachidonate 5 lipoxygenase enzyme, which transforms EFAs into… …   Wikipedia

  • lipoxygenase pathway — a pathway for the formation of leukotrienes and hydroxyeicosatetraenoic acids from arachidonic acid. It is initiated by oxidation of arachidonic acid by arachidonate lipoxygenases, and the reactions occur in the cytosol of leukocytes, mast cells …   Medical dictionary

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