methylene blue


methylene blue
A basic dye easily oxidized to azure, with dye mixtures; used in histology and microbiology, to stain intestinal protozoa in wet mount preparations, to track RNA and RNase in electrophoresis, and as an antidote for methemoglobinemia; its redox indicator properties are useful in milk bacteriology.
- Kühne m. m. in absolute alcohol and phenol solution.
- Loeffler m. a stain for diphtheria organisms that contains m. in dilute ethanol plus a slight amount of potassium hydroxide; dye solution gives best results when aged to a polychrome state.
- new m. [C.I. 52030] a basic thiazin dye used for supravital staining of reticulocytes in blood smears.
- polychrome m. an alkaline solution of m. that undergoes progressive oxidative demethylation with aging (ripening) to produce a mixture of m., azures, and methylene violet; boiling with sodium carbonate or other oxidizing agents accomplishes this result quickly, although it is not as highly regarded.

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methylene blue n a basic thiazine dye C16H18ClN3S·3H2O used in the treatment of methemoglobinemia, as an antidote in cyanide poisoning, as a biological stain, and as an oxidation-reduction indicator

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a blue dye used to stain bacterial cells for microscopic examination.

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[USP] methylthionine chloride; dark green crystals or crystalline powder having a bronzelike luster, readily reduced to colorless leukomethylene blue, which in turn is readily oxidized to methylene blue. Administered orally or intravenously in the treatment of congenital methemoglobinemia and intravenously in the treatment of toxic methemoglobinemia, and used as a bacteriological, biologic, and pathologic stain, as a colorimetric indicator for redox reactions, as a surgical marker, and as a diagnostic aid in the detection of the premature rupture of fetal membranes and to identify separate amniotic sacs in multiple pregnancies. Called also Swiss b.

Medical dictionary. 2011.

Look at other dictionaries:

  • Methylene blue — Methylene blue …   Wikipedia

  • Methylene blue — Methylene Meth yl*ene, n. [F. m[ e]thyl[ e]ne, from Gr. ? wine + ? wood; a word coined to correspond to the name wood spirit.] (Chem.) A divalent hydrocarbon radical, { CH2 }, not known in the free state, but regarded as an essential residue and… …   The Collaborative International Dictionary of English

  • methylene blue — n. a bluish green aniline dye, C16H18N3ClS·3H2O, used as a bacteriologic stain, an antidote in cyanide poisoning, etc …   English World dictionary

  • methylene blue — noun a dark green dye used as a stain, an antiseptic, a chemical indicator, and an antidote in cyanide poisoning • Syn: ↑methylthionine chloride • Hypernyms: ↑stain, ↑thiazine * * * noun Usage: sometimes capitalized M&B : a basic dye of the… …   Useful english dictionary

  • methylene blue — Chem., Pharm. a dark green, crystalline compound, C16H18ClN3S, that dissolves in water to form a deep blue solution: used chiefly as a dye, as a bacteriological and biological stain, and as an antidote for cyanide poisoning. Also called… …   Universalium

  • Methylene Blue — (= Swiss blue; Basic Blue 9; tetramethythionine chloride) Water soluble dye that can be reduced to a colourless form and can be oxidized by atmospheric oxygen. Used as a stain in bacteriology and histology …   Dictionary of molecular biology

  • methylene blue — meth′ylene blue′ n. pha chem. a dark green, crystalline compound, C16H18ClN3that dissolves in water to form a deep blue solution: used chiefly as a dye, as a biological stain, and as an antidote for cyanide poisoning …   From formal English to slang

  • methylene blue — a blue dye used to stain bacterial cells for microscopic examination …   The new mediacal dictionary

  • methylene blue — noun Date: circa 1890 a basic thiazine dye C16H18ClN3S•3H2O used especially as a biological stain, an antidote in cyanide poisoning, and an oxidation reduction indicator …   New Collegiate Dictionary

  • methylene blue — a dye (3,7 bis (Dimethylamino) phenazathionioum chloride) used against external bacteria and protozoans on fish …   Dictionary of ichthyology


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