myelocyte


myelocyte
1. A young cell of the granulocytic series, occurring normally in bone marrow, but not in circulating blood (except in certain diseases). When stained with the usual dyes, the cytoplasm is distinctly basophilic and relatively more abundant than in myeloblasts or promyelocytes, even though m.'s are smaller cells; numerous cytoplasmic granules ( i.e., neutrophilic, eosinophilic, or basophilic) are present in the more mature forms of m.'s, and the first two types are peroxidase-positive. The nuclear chromatin is coarser than that observed in myeloblasts, but it is relatively faintly stained and lacks a well defined membrane; the nucleus is fairly regular in contour ( i.e., not indented), and seems to be “buried” beneath the numerous cytoplasmic granules. 2. A nerve cell of the gray matter of the brain or spinal cord. SYN: medullocell. [myelo- + G. kytos, cell]
- m. A the youngest form of m., characterized by only a few (not more than ten) cytoplasmic granules, which are most reliably demonstrated by means of staining with neutral red; the mitochondria are numerous, and resemble those of the myeloblast.
- m. B the intermediate form of m., characterized by approximately 30–100 (or more) cytoplasmic granules scattered among the mitochondria; the latter are less numerous than in myelocytes of the A stage, and they are frequently displaced toward the periphery of the cell.
- m. C the most mature of the myelocytes characterized by numerous cytoplasmic granules that are recognizable as neutrophilic, eosinophilic, and basophilic; with neutral red these are stained, respectively, red, bright yellow, and deep maroon; C myelocytes are frequently larger than earlier forms; if the nucleus is indented, the m. is maturing into a metamyelocyte.

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my·e·lo·cyte 'mī-ə-lə-.sīt n a bone marrow cell esp a motile cell with cytoplasmic granules that gives rise to the blood granulocytes and occurs abnormally in the circulating blood (as in myelogenous leukemia)
my·e·lo·cyt·ic .mī-ə-lə-'sit-ik adj

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n.
an immature form of granulocyte having an oval nucleus (compare metamyelocyte) and neutrophil, eosinophil, or basophil granules within its cytoplasm (compare promyelocyte). It is normally found in the blood-forming tissue of the bone marrow, but may appear in the blood in a variety of diseases, including infections, infiltrations of the bone marrow, and certain leukaemias. See also granulopoiesis.

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my·elo·cyte (miґə-lo-sīt) [myelo- + -cyte] a precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, differentiation of cytoplasmic granules has begun, so that they are specifically basophilic, eosinophilic, or neutrophilic. myelocytic adj

Neutrophilic myelocyte (arrow).


Medical dictionary. 2011.

Look at other dictionaries:

  • Myelocyte — Code TH H2.00.04.3.04004 Basophilic[1 …   Wikipedia

  • myélocyte — [ mjelɔsit ] n. m. • 1855; de myélo et cyte ♦ Hématol. Cellule mère des leucocytes polynucléaires. ● myélocyte nom masculin Cellule médullaire de la lignée granulocytaire, dont le cytoplasme contient des granulations spécifiques (neutrophiles,… …   Encyclopédie Universelle

  • myelocyte — myelocyte. См. миелоцит. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • myelocyte — [mī′ə lō sīt΄] n. a type of large cell in the bone marrow, that develops into a granulocyte: it is present in the blood in some forms of leukemia myelocytic [mī΄ə lōsit′ik] adj …   English World dictionary

  • myelocyte — myelocytic /muy euh leuh sit ik/, adj. /muy euh leuh suyt /, n. Anat. a cell of the bone marrow, esp. one developing into a granulocyte. [1865 70; MYELO + CYTE] * * * ▪ biology       stage in the development of the granulocytic series of white… …   Universalium

  • myelocyte — noun Etymology: International Scientific Vocabulary Date: 1891 a bone marrow cell; especially a motile cell with cytoplasmic granules that gives rise to the granulocytes of the blood and occurs abnormally in the circulating blood • myelocytic… …   New Collegiate Dictionary

  • myelocyte — noun a) a large cell, found in bone marrow, that becomes a granulocyte when mature b) a cell associated with the myelin of the brain and spinal cord …   Wiktionary

  • myélocyte — (mi é lo si t ) s. m. Terme d anatomie. Éléments de la substance grise du système encéphalo rachidien. ÉTYMOLOGIE    Termes grecs signifiant moelle et cellule, loge …   Dictionnaire de la Langue Française d'Émile Littré

  • myelocyte — n. immature bone marrow cell (Anatomy) …   English contemporary dictionary

  • myelocyte — my·e·lo·cyte …   English syllables


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