- Gene silencing
- A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.
* * *negative regulation of gene expression; it includes processes that inhibit transcription of genes, such as DNA methylation, and posttranscriptional processes, such as the degradation of messenger RNA by RNA interference.
Medical dictionary. 2011.
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