neuraminidase


neuraminidase
SYN: sialidase.

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neur·amin·i·dase .n(y)u̇r-ə-'min-ə-.dās, -.dāz n a hydrolytic enzyme that occurs on the surface of the pneumococcus, the orthomyxoviruses, and some paramyxoviruses and that cleaves terminal acetylated neuraminic acids from sugar residues (as in glycoproteins and mucoproteins)

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neu·ra·min·i·dase (noor″ə-minґĭ-dās) an enzyme of the hydrolase class that catalyzes the cleavage of glucosidic linkages between a sialic acid residue and a hexose or hexosamine residue at the nonreducing terminal of oligosaccharides in glycoproteins, glycolipids, and proteoglycans. Cytosolic, plasma membrane, and lysosomal forms of the enzyme exist; deficiency of the latter, an autosomal recessive trait, causes sialidosis; enzyme activity is also lacking in galactosialidosis. Viral neuraminidase found on the surface of influenza viruses enables viral release from the host cell. In EC nomenclature, called exo-α-sialidase. Called also sialidase.

Medical dictionary. 2011.

Look at other dictionaries:

  • Neuraminidase — Bezeichner Gen Namen …   Deutsch Wikipedia

  • Neuraminidase — Neuraminic acid Neuraminidase enzymes are glycoside hydrolase enzymes (EC 3.2.1.18) that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The most commonly known… …   Wikipedia

  • Neuraminidase — Pour les articles homonymes, voir N1, N2, N3, N4, N5, N6, N7, N8 et N9 …   Wikipédia en Français

  • neuraminidase — (= sialidase) Enzyme catalysing cleavage of neuraminic acid residues from oligosaccharide chains of glycoproteins and glycolipids. Since these residues are usually terminal, neuraminidases are generally exo enzymes, although an endoneuraminidase… …   Dictionary of molecular biology

  • neuraminidase — noun Etymology: neuraminic acid, an amino acid + ide + ase Date: 1957 a hydrolytic enzyme that occurs on the surface of the pneumococcus, influenza causing viruses, and some paramyxoviruses as an antigen and that splits mucoproteins by breaking a …   New Collegiate Dictionary

  • neuraminidase — neu·ra·min·i·dase (no͝or ə mĭnʹĭ dās , dāz , nyo͝or ) n. A hydrolytic enzyme that removes sialic acid from mucoproteins and is found chiefly in microorganisms of the respiratory and intestinal tracts.   [neuramin(ic acid)(neuro + amine) + ide +… …   Universalium

  • neuraminidase — noun An antigenic enzyme, found on the surfaces of viruses, that catalyzes the hydrolysis of terminal acylneuraminic residues from oligosaccharides, glycoproteins, and glycolipids …   Wiktionary

  • Neuraminidase — Neu|r|a|mi|ni|dase [Kurzw. aus ↑ Neuraminsäure u. ↑ Glykosidase] Syn.: Acylneuraminylhydrolase, Sialidase: Gruppenbez. für in pathogenen Mikroorganismen, Lysosomen, Spermafl. usw. vorkommende Glykosidasen, die neuraminsäurehaltige Glykolipide (z …   Universal-Lexikon

  • neuraminidase — neur·amin·i·dase …   English syllables

  • neuraminidase —  n.f. Enzyme …   Le dictionnaire des mots absents des autres dictionnaires


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