osteodystrophy


osteodystrophy
Defective formation of bone. SYN: osteodystrophia. [osteo- + G. dys, difficult, imperfect, + trophe, nourishment]
- Albright hereditary o. an inherited form of hyperparathyroidism associated with ectopic calcification and ossification and skeletal defects, notably the small fourth metacarpals; intelligence may be normal or subnormal. Inheritance is heterogeneous; the autosomal form [MIM*103580] is caused by mutation in the guanine nucleotide-binding protein gene (GNAS1) on 20q. There are also the recessive [MIM*203330] and X-linked [MIM*300800] forms. SEE ALSO: pseudohypoparathyroidism. SYN: Albright syndrome (2).
- renal o. generalized bone changes resembling osteomalacia and rickets or osteitis fibrosa, occurring in children or adults with chronic renal failure.

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os·teo·dys·tro·phy -'dis-trə-fē n, pl -phies defective ossification of bone usu. associated with disturbed calcium and phosphorus metabolism

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n.
any generalized bone disease resulting from a metabolic disorder. In renal osteodystrophy chronic kidney failure leads to diffuse bone changes resulting from osteomalacia, secondary hyperparathyroidism (excessive secretion of parathyroid hormone), osteoporosis, and osteosclerosis. See also Albright's hereditary osteodystrophy.

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os·teo·dys·tro·phy (os″te-o-disґtrə-fe) defective bone formation.

Medical dictionary. 2011.

Look at other dictionaries:

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  • osteodystrophy — n. any generalized bone disease resulting from a metabolic disorder. In renal osteodystrophy chronic kidney failure leads to diffuse bone changes resulting from osteomalacia, secondary hyperparathyroidism (excessive secretion of parathyroid… …   The new mediacal dictionary

  • osteodystrophy — noun Any abnormal or defective development of a bone …   Wiktionary

  • osteodystrophy — os·teo·dystrophy …   English syllables

  • osteodystrophy — noun defective bone development; usually attributable to renal disease or to disturbances in calcium and phosphorus metabolism • Hypernyms: ↑dystrophy …   Useful english dictionary

  • Osteodystrophy, renal — A bone growth disorder caused by chronic kidney failure (renal disease). Also …   Medical dictionary

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  • renal osteodystrophy — ▪ pathology also called  renal rickets        chronic, probably hereditary disorder characterized by kidney dysfunction, bone mineral loss and rickets type deformities, calcifications in abnormal places, and overactivity of the parathyroid glands …   Universalium