phosphatidic acid


phosphatidic acid
1,2-Diacylglycerol phosphate; a derivative of glycerophosphoric acid in which the two remaining hydroxyl groups of the glycerol are esterified with fatty acid s; e.g., phosphatidic acid s attached to choline are phosphatidylcholines (lecithins).

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phosphatidic acid n any of several acids (RCOO)2C3H5OPO3H2 that are formed from phosphatides by partial hydrolysis and that yield on hydrolysis two fatty-acid molecules RCOOH and one molecule each of glycerol and phosphoric acid

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phos·pha·ti·dic ac·id (fos″fə-tiґdik) glycerol esterified with long-chain fatty acyl groups at C1 and C2 and phosphorylated at C3; it is the simplest phosphoglyceride (q.v.), the parent compound of most important membrane phospholipids, and a key intermediate in the biosynthesis and degradation of many phosphoglycerides.

Medical dictionary. 2011.

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  • Phosphatidic acid — Chembox new ImageFile = Phosphatidate2.png ImageSize = IUPACName = OtherNames = 1,2 Diacylglycerol 3 phosphate, phosphatidic acid Section1 = Chembox Identifiers CASNo = PubChem = 5460104 SMILES = MeSHName = Phosphatidic+Acids Section2 = Chembox… …   Wikipedia

  • phosphatidic acid — noun Etymology: phosphatidic from phosphatide + ic : any of several acids (RCOO)2C3H5OPO3H2 that are formed from phosphatides by partial hydrolysis (as by removal of the nitrogen base), that are glycerides of glycerophosphoric acids, and that… …   Useful english dictionary

  • phosphatidic acid — /fɒsfəˌtaɪdɪk ˈæsəd/ (say fosfuh.tuydik asuhd) noun the parent acid for many phospholipids, containing laevoglycerol esterified with two fatty acid residues and phosphoric acid …   Australian English dictionary

  • phosphatidic acid — noun any derivative of glycerol in which one hydroxyl is esterified with phosphoric acid and the other two are esterified with fatty acids …   Wiktionary

  • phosphatidic acid — (= PA; diacyl glycerol 3 phosphate) The ‘parent’ structure for phosphatidyl phospholipids, present in low concentrations in membranes. The acyl groups are derived from long chain fatty acids. An intermediate in the synthesis of diacyl glycerol,… …   Dictionary of molecular biology

  • Phosphatidic acid phosphatase 2c — Phosphatidic acid phosphatase type 2C, also known as PPAP2C, is a human gene.cite web | title = Entrez Gene: PPAP2C phosphatidic acid phosphatase type 2C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • lysophosphatidic acid — A phosphatidic acid in which only one of the two hydroxyl groups of the glycerophosphate is esterified; most commonly, when carbon 1 of the glycerol moiety is esterified ( e.g., 1 acylglycerol 3 phosphate). l. acyltransferase, 1 acylglycerol 3… …   Medical dictionary

  • Lysophosphatidic acid — Chembox new ImageFile = Lysophosphatidic acid.svg‎ ImageSize = 250px IUPACName = (2 hydroxy 3 phosphonooxypropyl) (Z) octadec 9 enoate OtherNames = LPA Section1 = Chembox Identifiers CASNo = 22002 87 5 PubChem = 5497152 SMILES =… …   Wikipedia

  • PPAP2A — Phosphatidic acid phosphatase type 2A, also known as PPAP2A, is a human gene.cite web | title = Entrez Gene: PPAP2A phosphatidic acid phosphatase type 2A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • PPAP2B — Phosphatidic acid phosphatase type 2B, also known as PPAP2B, is a human gene.cite web | title = Entrez Gene: PPAP2B phosphatidic acid phosphatase type 2B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia