phytanic acid

phytanic acid
A branched-chain fatty acid that accumulates in the serum and tissues in Refsum disease and attributed to the hereditary absence of phytanate α-oxidase; arises from phytol and acts as an inhibitor of the α-oxidation of palmitic (hexadecanoic) acid; it also accumulates in a number of other disorders, notably peroxisomal disorders.

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phy·tan·ic acid fī-.tan-ik- n a fatty acid derived from phytol that accumulates in the blood and tissues of patients affected with Refsum's disease

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phy·tan·ic ac·id (fi-tanґik) an unusual 20-carbon branched-chain fatty acid found at high levels in dairy products and fatty tissue of ruminants, and accumulated in tissues of patients with Refsum disease and several peroxisomal disorders.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Phytanic acid — Chembox new ImageFile = Phytanic acid.png ImageSize = 250px IUPACName = ( 7R,11R ) 3,7,11,15 Tetramethylhexadecanoic acid OtherNames = phytanoic acid Section1 = Chembox Identifiers CASNo = 14721 66 5 PubChem = 468706 SMILES = CC(C)CCC [C@@H]… …   Wikipedia

  • Phytanic acid storage disease (Refsum’s disease) — A genetic disorder of the fatty acid phytanic acid which accumulates and causes a number of progressive problems including polyneuritis (inflammation of numerous nerves), diminishing vision (due to retinitis pigmentosa), and wobbliness (ataxia)… …   Medical dictionary

  • phytanic acid storage disease — 1. Refsum d. 2. any of several disorders characterized by abnormal accumulation of phytanic acid in tissues …   Medical dictionary

  • phytanic acid α-hydroxylase — phy·tan·ic ac·id α hy·droxy·lase (fi tanґik asґid hi drokґsə lās) an enzyme that catalyzes the alpha oxidation of phytanic acid, hydroxylating its alpha carbon; the reaction requires molecular oxygen and is stimulated by NADPH and… …   Medical dictionary

  • phytanic acid — noun The diterpenoid acid (7R,11R) 3,7,11,15 tetramethylhexadecanoic acid derived from chlorophyll via the related phytol …   Wiktionary

  • Disease, phytanic acid storage (Refsum’s disease) — A genetic disorder of the fatty acid phytanic acid which accumulates and causes a number of progressive problems including polyneuritis (inflammation of numerous nerves), diminishing vision (due to retinitis pigmentosa), and wobbliness (ataxia)… …   Medical dictionary

  • phytanic — adjective Of or pertaining to phytanic acid or its derivatives …   Wiktionary

  • Pristanic acid — Chembox new ImageFile=PristanicAcid.png ImageSize= IUPACName=2,6,10,14 tetramethylpentadecanoic acid OtherNames= Section1= Chembox Identifiers CASNo=1189 37 3 PubChem=123929 SMILES=CC(C)CCCC(C)CCCC(C)CCCC(C)C(=O)O Section2= Chembox Properties… …   Wikipedia

  • Refsum disease — Classification and external resources Phytanic acid ICD 10 G60.1 …   Wikipedia

  • Refsum's disease — Infobox Disease Name = PAGENAME Caption = Phytanic acid DiseasesDB = 11213 ICD10 = ICD10|G|60|1|g|60 ICD9 = ICD9|356.3 ICDO = OMIM = 266500 MedlinePlus = eMedicineSubj = derm eMedicineTopic = 705 MeshID = D012035 Refsum s disease (Refsum Thiébaut …   Wikipedia

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