plasmacytoma


plasmacytoma
A discrete, presumably solitary mass of neoplastic plasma cells in bone or in one of various extramedullary sites; in humans, such lesions are probably the initial phase of developing plasma cell myeloma. [plasmacyte + G. -oma, tumor]

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plas·ma·cy·to·ma also plas·mo·cy·to·ma .plaz-mə-sī-'tō-mə n, pl -mas also -ma·ta -mət-ə a myeloma composed of plasma cells

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n.
a malignant tumour of plasma cells, often known as a 'solitary myeloma'. Although usually occurring as a single tumour in bone marrow or more rarely soft tissue (extramedullary plasmacytoma), it may be multiple, in which case it is classified as a multiple myeloma. All of these tumours may produce the abnormal gammaglobulins that are characteristic of myeloma, and they may progress to widespread myeloma. The soft-tissue tumours often respond to radiotherapy and to such drugs as melphalan and cyclophosphamide; the bone tumours are less responsive. Tumours originating in soft tissue (usually the airways) may spread to bone, producing an appearance on X-ray identical to myeloma deposits; these secondary growths often resolve completely after treatment.

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plas·ma·cy·to·ma (plaz″mə-si-toґmə) [plasmacyte + -oma] 1. plasma cell dyscrasias. 2. solitary myeloma.

Medical dictionary. 2011.

Look at other dictionaries:

  • Plasmacytoma — See also: Multiple myeloma Plasmacytoma Classification and external resources Micrograph of a plasmacytoma. H E stain. ICD …   Wikipedia

  • plasmacytoma — Malignant tumour of plasma cells, very similar to a myeloma (plasmacytomas usually develop into multiple myeloma). Can easily be induced in rodents by the injection of complete Freund s adjuvant. Plasmacytoma cells are fused with primed… …   Dictionary of molecular biology

  • plasmacytoma — n. a malignant tumour of plasma cells, often known as a solitary myeloma . Although usually occurring as a single tumour in bone marrow or more rarely soft tissue (extramedullary plasmacytoma), it may be multiple, in which case it is classified… …   The new mediacal dictionary

  • plasmacytoma — A type of cancer that begins in plasma cells (white blood cells that produce antibodies). A plasmacytoma may turn into multiple myeloma …   English dictionary of cancer terms

  • plasmacytoma — noun A malignant tumour of plasmacytes …   Wiktionary

  • plasmacytoma — plas·ma·cy·to·ma …   English syllables

  • plasmacytoma — noun neoplasm of plasma cells (usually in bone marrow) • Hypernyms: ↑tumor, ↑tumour, ↑neoplasm …   Useful english dictionary

  • Плазмоцитома (Plasmacytoma) — злокачественная опухоль плазматических клеток, по своему происхождению тесно связанная с миеломой. Обычно развивается как одиночная опухоль кости, однако иногда она может быть и множественной. Реже эта опухоль поражает мягкие ткани (обычно… …   Медицинские термины

  • multiple plasmacytoma of bone — multiple myeloma …   Medical dictionary

  • ПЛАЗМОЦИТОМА — (plasmacytoma) злокачественная опухоль плазматических клеток, по своему происхождению тесно связанная с миеломой. Обычно развивается как одиночная опухоль кости, однако иногда она может быть и множественной. Реже эта опухоль поражает мягкие ткани …   Толковый словарь по медицине


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