Hirudin

Hirudin
An anti-clotting agent that prevents blood clots from traveling through the blood stream to clog up a vessel (thromboembolic complications). Hirudin is the active principle in the secretion of leeches. Desirudin and lepirudin (brand name: Refludan) are genetically engineered recombinant forms of hirudin.
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An antithrombin substance extracted from the salivary glands of the leech that has the property of preventing coagulation of the blood. [L. hirudo, leech]

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hi·ru·din hir-'üd-ən, 'hir-(y)əd-ən n an anticoagulant extracted from the buccal glands of a leech

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n.
an anticoagulant present in the salivary glands of leech and in certain snake venoms, that prevents blood coagulation by inhibiting the action of the enzyme thrombin.

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hi·ru·din (hĭ-rooґdin) [L. hirudo leech] the active principle of the secretion of the buccal glands of leeches, which prevents coagulation of the blood by acting as an antithrombin; hirudin prepared by recombinant technology is a direct thrombin inhibitor that is used as an anticoagulant.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Hirudin — 1 (Hirudo medicinalis) Modell von Hirudin (Stäbchen) im K …   Deutsch Wikipedia

  • hirudin — [hir′yo͞o din΄] n. [orig. a trademark: < L hirudo, leech + IN1] a substance found in the salivary glands of leeches that prevents the coagulation of blood …   English World dictionary

  • Hirudin — Structure of Hirudin in complex with Thrombin.[1] Hirudin …   Wikipedia

  • Hirudin — Hi|ru|din 〈n.; s; unz.; Pharm.〉 Extrakt aus dem Kopf u. dem Schlund von Blutegeln, verzögert die Blutgerinnung [zu lat. hirudo „Blutegel“] * * * Hi|ru|din [lat. hirudo = Blutegel; ↑ in (3)], das; s, e: aus Blutegeln isolierbares, auch… …   Universal-Lexikon

  • hirudin — noun Etymology: from Hirudin, a trademark Date: 1905 an anticoagulant extracted from the buccal glands of the medicinal leech …   New Collegiate Dictionary

  • hirudin — ˈhir(y)ədə̇n, hə̇ˈrüdən noun ( s) Etymology: from Hirudin, a trademark : a preparation of the active principles of the buccal glands of a leech used to retard or prevent the clotting of blood …   Useful english dictionary

  • hirudin — /hir yeuh din, hir euh , hi roohd n/, n. a gray or white, water soluble acidic polypeptide obtained from the buccal gland of leeches, used in medicine chiefly as an anticoagulant. [1900 05; formerly trademark] * * * …   Universalium

  • hirudin — noun A peptide, obtained from the salivary glands of leeches, that is used as an anticoagulant See Also: hirudinal …   Wiktionary

  • Hirudin — Hi|ru|din 〈n.; Gen.: s; Pl.: unz.〉 Extrakt aus dem Kopf u. Schlund von Blutegeln, verzögert die Blutgerinnung [Etym.: <lat. hirudo »Blutegel«] …   Lexikalische Deutsches Wörterbuch

  • Hirudin — Hirudi̱n [zu ↑Hirudo] s; s: in den Speicheldrüsen des Blutegels enthaltener, die Blutgerinnung hemmender Stoff …   Das Wörterbuch medizinischer Fachausdrücke

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