prednisolone

prednisolone
A dehydrogenated analog of cortisol with the same actions and uses as cortisol; a potent glucocorticoid.
- p. acetate same uses as p.; suitable for intramuscular administration.
- p. butylacetate SYN: p. tebutate.
- p. sodium phosphate more soluble than p. and the other p. esters and useful when a rapid onset or a short duration of action is desired; suitable for intrasynovial, parenteral, and topical administration.
- p. succinate p. compound suitable for intramuscular, intravenous, or rectal administration.
- p. tebutate same actions and uses as p. but with longer duration of action and suitable for intrasynovial and soft tissue injection. SYN: p. butylacetate.

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pred·nis·o·lone pred-'nis-ə-.lōn n a glucocorticoid C21H28O5 that is a dehydrogenated analog of cortisol and is used often in the form of an ester or methyl derivative esp. as an anti-inflammatory drug in the treatment of arthritis

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n.
a synthetic corticosteroid used to treat rheumatic diseases, inflammatory and allergic conditions, and some cancers (e.g. leukaemia, lymphoma). It is administered by mouth, injected into joints, or applied in creams, lotions, ointments, or drops (to treat skin, eye, or ear conditions). Side-effects are those of cortisone. Trade names: Deltacortril, Deltastab, Precortisyl, Prednesol, Predsol.

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pred·nis·o·lone (pred-nisґə-lōn″) [USP] a synthetic glucocorticoid derived from cortisol, administered orally in replacement therapy for adrenocortical insufficiency and as an antiinflammatory and immunosuppressant in a wide variety of conditions.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Prednisolone — Systematic (IUPAC) name (11β) …   Wikipedia

  • Prednisolone — Général No CAS …   Wikipédia en Français

  • prednisolone — ● prednisolone nom féminin Médicament corticoïde dérivé de l hydrocortisone et possédant un pouvoir anti inflammatoire plus élevé que celle ci. ● prednisolone (synonymes) nom féminin Médicament corticoïde dérivé de l hydrocortisone et possédant… …   Encyclopédie Universelle

  • prednisolone acetate — [USP] the 21 acetate ester of prednisolone, administered by intramuscular injection in replacement therapy for adrenocortical insufficiency and by intra articular, intralesional, or soft tissue injection as an antiinflammatory and… …   Medical dictionary

  • prednisolone sodium phosphate — [USP] a water soluble ester of prednisolone, having a rapid onset and short duration of action; administered orally or by intramuscular injection in replacement therapy for adrenocortical insufficiency, orally or by intravenous, intramuscular,… …   Medical dictionary

  • prednisolone sodium succinate — [USP] a water soluble ester of prednisolone, used as a glucocorticoid …   Medical dictionary

  • prednisolone tebutate — [USP] an ester of prednisolone having a slow onset and long duration of action, used as an antiinflammatory and immunosuppressant; administered by intra articular, intralesional, or soft tissue injection …   Medical dictionary

  • prednisolone — noun Etymology: blend of prednisone and 1 ol Date: 1955 a glucocorticoid C21H28O5 that is a dehydrogenated analog of cortisol and is used especially as an anti inflammatory drug …   New Collegiate Dictionary

  • prednisolone — (= 1,4 pregnadiene 11b,17a, 21 triol 3,20 dione) Steroid with glucocorticoid action, very similar to prednisone. An effective anti inflammatory drug but with serious side efects …   Dictionary of molecular biology

  • prednisolone — /pred nis euh lohn /, n. Pharm. a synthetic glucocorticoid, C21H28O5, used in various forms to treat inflammation and allergies and in the treatment of acute leukemia, Hodgkin s disease, and lymphomas. [1950 55; alter. of PREDNISONE by insertion… …   Universalium

  • prednisolone — noun A synthetic glucocorticoid steroid, similar to hydrocortisone, used as an anti inflammatory, immunosuppressive, and antiallergic drug …   Wiktionary

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