A small protein that binds to monomeric actin (thus becoming profilactin), preventing premature polymerization of actin. It also participates in the inhibition of one isoform of phospholipase C.

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pro·fil·in (pro-filґin) a 15-kD actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin. It also binds to phosphatidylinositol bisphosphate, providing a link between actin organization and signal transduction. See also gelsolin and thymosin β4>.

Medical dictionary. 2011.

Look at other dictionaries:

  • Profilin — is an actin binding protein involved in the dynamic turnover and restructuring of the actin cytoskeleton. It is found in all eukaryotic organisms in most cells. Profilin is important for spatially and temporally controlled growth of actin… …   Wikipedia

  • Profilin 1 — Profilin 1, also known as PFN1, is a human gene. PBB Summary section title = summary text = The protein encoded by this gene is a ubiquitous actin monomer binding protein belonging to the profilin family. It is thought to regulate actin… …   Wikipedia

  • Profilin — 1 Bändermodell von Profilin 1 (blau) gebunden an Aktin (grün), nach …   Deutsch Wikipedia

  • profilin — profilin. См. профилин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • profilin — Actin binding protein (15 kD) that forms a complex with G actin rendering it incompetent to nucleate F actin formation. The profilin actin complex seems to interact with inositol phospholipids that may regulate the availability of nucleation… …   Dictionary of molecular biology

  • profilin — …   Useful english dictionary

  • PFN2 — Profilin 2, also known as PFN2, is a human gene.cite web | title = Entrez Gene: PFN2 profilin 2| url = Cmd=ShowDetailView TermToSearch=5217| accessdate = ] PBB Summary section title = summary text …   Wikipedia

  • профилин — profilin профилин. Небольшой цитоплазматический белок, участвующий в контроле скорости и уровня полимеризации актина <actin> в клетке, поддержании его стабильности, образовании комплекса АТФ актин (доказано для тромбоцитов человека) и др.;… …   Молекулярная биология и генетика. Толковый словарь.

  • Thymosin — protein Name = thymosin, beta 4, X linked caption = width = HGNCid = 11881 Symbol = TMSB4X AltSymbols = TMSB4 EntrezGene = 7114 OMIM = 300159 RefSeq = NM 021109 UniProt = P62328 PDB = ECnumber = Chromosome = X Arm = q Band = 21.3… …   Wikipedia

  • Pascal Goldschmidt — Pascal J. Goldschmidt Clermont, M.D., is a Belgian born, American cardiologist, and is the Senior Vice President for Medical Affairs and the Dean of the Miller School of Medicine at the University of Miami. He was previously the Edward S. Orgain… …   Wikipedia

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