prolyl


prolyl
- p. dipeptidase an enzyme cleaving l-p.-amino acid bonds in dipeptides containing N-terminal p. residues. SYN: iminodipeptidase, prolinase, prolylglycine dipeptidase.
- p. hydroxylase an enzyme that catalyzes the hydroxylation of certain p. residues in collagen precursors using molecular oxygen, ferrous ion, ascorbic acid, and α-ketoglutarate; a vitamin C deficiency directly affects the activity of this enzyme; one form of this enzyme (p. 4-hydroxylase) synthesizes 4-hydroxyprolyl residues while another produces 3-hydroxyprolyl residues.

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pro·lyl 'prō-.lil n the amino acid radical or residue C4H8NCO- of proline abbr. Pro

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pro·lyl (proґləl) the acyl radical of proline.

Medical dictionary. 2011.

Look at other dictionaries:

  • prolyl- — prolil statusas T sritis chemija apibrėžtis Grupė. formulė NC₄H₈CO– atitikmenys: angl. prolyl rus. пролил ryšiai: sinonimas – 2 pirolidinkarbonil …   Chemijos terminų aiškinamasis žodynas

  • prolyl — noun The univalent radical derived from proline …   Wiktionary

  • prolyl — pro·lyl …   English syllables

  • prolyl — ˈprōˌlil noun ( s) Etymology: International Scientific Vocabulary proline + yl : the univalent acid radical C4H8NCO− of proline …   Useful english dictionary

  • Prolyl isomerase — (also PPIase) is an enzyme found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline. Proline has an unusually conformationally restrained peptide bond due to its cyclic… …   Wikipedia

  • Prolyl hydroxylase — (or procollagen proline dioxygenase) is an enzyme involved in the production of collagen, acting to hydroxylate proline to hydroxyproline.It requires vitamin C as a cofactor.Reaction: Proline + α ketoglutarate + O2 + Fe2+ → 4 hydroxyproline +… …   Wikipedia

  • prolyl 4-hydroxylase — prolyl 4 hydroxylase. См. пролил 4 гидроксилаза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Prolyl-4-Hydroxylase — Die Prolyl 4 Hydroxylase (4 PH) (auch: Procollagenprolin Dioxygenase) ist ein Enzymkomplex in Wirbeltieren, der die Hydroxylierung von Prolylresten in Proteinen katalysiert. Dabei handelt es sich um eine posttranslationale Modifikation. Sie ist… …   Deutsch Wikipedia

  • Prolyl endopeptidase — [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600400 Prolyl endopeptidase] (PREP) or prolyl oligopeptidase (EC number|3.4.21.26), sometimes post proline cleaving enzyme) is a large cytosolic enzyme that belongs to a distinct class of serine …   Wikipedia

  • prolyl hydroxylase — See hydroxyproline …   Dictionary of molecular biology


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