- Overgrowth of bone. Hyperostosis is a nonspecific term that does not refer to any particular condition.
* * *- h. corticalis deformans [MIM*239000] marked irregular thickening of the skull and bone cortex, with thickening and widening of the shafts of long bones and high serum alkaline phosphatase; autosomal recessive inheritance.- diffuse idiopathic skeletal h. (DISH) a generalized spinal and extraspinal articular disorder characterized by calcification and ossification of ligaments, particularly of the anterior longitudinal ligament; distinct from ankylosing spondylitis or degenerative joint disease. SYN: ankylosing h., Forestier disease, hyperostotic spondylosis.- flowing h. SYN: rheostosis.- h. frontalis interna abnormal deposition of bone on the inner aspect of the os frontale, visible by x-ray; may be a part of Morgagni syndrome.- infantile cortical h. [MIM*114000] neonatal subperiosteal bone formation over many bones, especially the mandible, clavicles, and the shafts of long bones; it follows fever, usually appearing before 6 months of age and disappearing during childhood; familial cases are inherited as autosomal dominant. SYN: Caffey disease, Caffey syndrome, Caffey-Silverman syndrome.
* * *hy·per·os·to·sis .hī-pə-.räs-'tō-səs n, pl -to·ses -'tō-.sēz excessive growth or thickening of bone tissuehy·per·os·tot·ic -'tät-ik adj
* * *n.excessive enlargement of the outer layer of a bone. The condition is harmless and is usually recognized as an incidental finding on X-ray. It commonly affects the frontal bone of the skull (hyperostosis frontalis). Infantile cortical hyperostosis (or Caffey's disease) affects infants under six months. There is swelling of the long bones, jaw, and shoulder blade, with pain and a fever. The condition settles spontaneously.
* * *hy·per·os·to·sis (hi″pər-os-toґsis) [hyper- + osteo- + -osis] hypertrophy of bone; cf. exostosis. hyperostotic adj
Medical dictionary. 2011.