An acute pulmonary disorder, radiographically and histologically similar to pulmonary alveolar proteinosis, resulting from relatively short exposure to high concentrations of silica dust; pulmonary symptoms are of rapid onset and the condition is invariably fatal.

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sil·i·co·pro·tein·o·sis (sil″ĭ-ko-pro″tēn-oґsis) a rapidly fatal pneumoconiosis occurring several weeks to months after massive exposure to silica dust, characterized by the presence of proteinaceous fluid in the air spaces.

Medical dictionary. 2011.

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