squalene


squalene
A hexaisoprenoid (triterpenoid) hydrocarbon found in shark oil and in some plants; intermediate in the biosynthesis of cholesterol and other sterols and triterpenes.
- s. epoxidase an enzyme that catalyzes the conversion of s. to s. 2,3-oxide in the endoplasmic reticulum; a required step in order for cyclization to occur, resulting in the synthesis of the first sterol, lanosterol, in steroidogenesis; uses NADPH.
- s. synthase an enzyme that catalyzes the formation of s. from two molecules of farnesylpyrophosphate using NADPH and concomitant production of two molecules of pyrophosphate.

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squa·lene 'skwā-.lēn n an acyclic hydrocarbon C30H50 that is widely distributed in nature (as a major component of sebum and in shark-liver oils) and is a precursor of sterols (as cholesterol)

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n.
an unsaturated hydrocarbon (a terpene), synthesized in the body, from which cholesterol is derived.

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squa·lene (skwaґlēn) [first isolated from Squalus, a genus of sharks] an unsaturated, symmetrical, 30-carbon triterpene intermediate formed in the biosynthesis of cholesterol and all other cyclic triterpenes. It can be isolated from shark and other fish oils and some plants.

Medical dictionary. 2011.

Look at other dictionaries:

  • Squalène — Structure du Squalène, un terpène …   Wikipédia en Français

  • Squalene — Squalène Squalène Structure du Squalène, un terpène …   Wikipédia en Français

  • squalène — ● squalène nom masculin Hydrocarbure insaturé, liquide, contenu dans de nombreux tissus animaux (foie de squales) et végétaux, pivot de la biosynthèse des stérols. squalène [skwalɛn] n. m. ÉTYM. Mil. XXe (in Larousse, 1949); de squale, parce que… …   Encyclopédie Universelle

  • squalene — [skwā′lēn΄] n. [< ModL Squalus, a genus of sharks (< L, a kind of sea fish: see WHALE1) + ENE] an unsaturated hydrocarbon, C30H50, found in shark livers, etc. that is a precursor of cholesterol in biosynthesis …   English World dictionary

  • Squalene — Chembox new Name = Squalene ImageFile = Squalene.svg ImageSize = 350px ImageName = Skeletal formula of squalene IUPACName = 2,6,10,15,19,23 hexamethyl 2,6,10,14,18,22 tetracosahexaene Section1 = Chembox Identifiers CASNo = 111 02 4 SMILES = CC(C) …   Wikipedia

  • Squalene — Strukturformel Allgemeines Name Squalen Andere Namen 2,6,10,15,19,23 Hexamethyl 2,6,10,14,18,22 tetracosahexaen Spinacen Suprae …   Deutsch Wikipedia

  • squalene — skvalenas statusas T sritis chemija apibrėžtis Alifatinis triterpenas. formulė C₃₀H₅₀ atitikmenys: angl. squalene rus. сквален …   Chemijos terminų aiškinamasis žodynas

  • squalene — noun Etymology: International Scientific Vocabulary, from Latin squalus, a sea fish more at whale Date: 1916 an acyclic hydrocarbon C30H50 that is widely distributed in nature (as a major component of sebum and in shark liver oils) and is a… …   New Collegiate Dictionary

  • squalene — a low specific gravity hydrocarbon found in the livers of squaloid sharks and used in cosmetics, lipsticks, hair setting preparations, moisturizers and lubricants for fine machinery …   Dictionary of ichthyology

  • squalene — /skway leen/, n. Biochem. an oil, C30H50, intermediate in the synthesis of cholesterol, obtained for use in manufacturing pharmaceuticals. [1925 30; < NL Squal(us) name of a genus of sharks (the liver of which yields the oil), L: a kind of fish + …   Universalium

  • squalene — noun A triterpene hydrocarbon found in shark liver oil and in human sebum; it plays a role in the biosynthesis of steroids …   Wiktionary