tolbutamide
An orally active hypoglycemic agent used in the management of adult-onset diabetes mellitus; it appears to stimulate the synthesis and release of endogenous insulin from functional islets; available as t. sodium for injection.

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tol·bu·ta·mide täl-'byüt-ə-.mīd n a sulfonylurea C12H18N2O3S used orally to lower blood sugar in the treatment of type 2 diabetes

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n.
a drug taken by mouth in the treatment of noninsulin-dependent diabetes mellitus. It acts directly on the pancreas to stimulate insulin production and is particularly effective in elderly patients with mild diabetes (see sulphonylurea). Side-effects are similar to those of the sulphonamide and include skin reactions and transient jaundice.

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tol·bu·ta·mide (tol-buґtə-mīd) [USP] a sulfonylurea compound used as a hypoglycemic in the treatment of type 2 diabetes mellitus; administered orally.

Medical dictionary. 2011.

Look at other dictionaries:

  • Tolbutamide — Systematic (IUPAC) name N [(butylamino)carbonyl] 4 methylbenzenesulfonamide Clinical data AHFS/Drugs.com …   Wikipedia

  • tolbutamide — [ tɔlbytamid ] n. m. • v. 1960; de tol(yle), but(yle) et amide ♦ Méd. Sulfamide administré par voie buccale dans le traitement du diabète. ● tolbutamide ou tolglybutamide nom masculin Dénomination courante d un sulfamide hypoglycémiant …   Encyclopédie Universelle

  • tolbutamide — ☆ tolbutamide [täl byo͞ot′ə mīd΄ ] n. [ TOL(U) + BUT(YRIC) + AMIDE] an oral drug, C12H18N2O3S, that stimulates the pancreas to secrete more insulin, used to treat diabetes …   English World dictionary

  • tolbutamide — /tol byooh teuh muyd /, n. Pharm. a white crystalline substance, C12H18N2O3S, used to augment insulin secretion in the treatment of diabetes mellitus. [1955 60; TOL(U) + BUT(YL) + AMIDE] * * * ▪ drug       drug used in the treatment of type II… …   Universalium

  • tolbutamide — noun Etymology: tol + butyric + amide Date: 1956 a sulfonylurea C12H18N2O3S used in the treatment of diabetes …   New Collegiate Dictionary

  • tolbutamide — A sulphonylurea that will bind to SUR and enhance insulin release from pancreatic B cells. Used in Type II diabetes (as are a number of similar drugs) …   Dictionary of molecular biology

  • tolbutamide — noun A drug that blocks potassium channels, used in the treatment of diabetes …   Wiktionary

  • tolbutamide — tol·bu·ta·mide …   English syllables

  • tolbutamide — n. a drug taken by mouth in the treatment of type 2 diabetes mellitus. It acts directly on the pancreas to stimulate insulin production and is particularly effective in elderly patients with mild diabetes (see sulphonylurea). Side effects may… …   The new mediacal dictionary

  • tolbutamide — noun sulfonylurea; an oral antidiabetic drug (trade name Orinase) used in the treatment of adult onset diabetes mellitus • Syn: ↑Orinase • Usage Domain: ↑trade name (for: ↑Orinase) • Hypernyms: ↑sulfonylure …   Useful english dictionary

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