tuberculin

tuberculin
1. A glycerin-broth culture of Mycobacterium tuberculosis evaporated to 110 volume at 100°C and filtered; introduced by Robert Koch for the treatment of tuberculosis but now used chiefly for diagnostic tests; originally known as Koch old t. (OT) or Koch original t. 2. One or another of a relatively large number of extracts of Mycobacterium tuberculosis cultures, different from OT and now obsolete.
- Koch old t. (OT) t. (1).
- purified protein derivative of t. (PPD) purified t. containing the active protein fraction; the t. from which it is prepared differs from t. (1) chiefly in that the bacteria are grown in a synthetic rather than in a broth medium.

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tu·ber·cu·lin t(y)u̇-'bər-kyə-lən n a sterile solution containing the growth products of or specific substances extracted from the tubercle bacillus and used in the diagnosis of tuberculosis see old tuberculin, purified protein derivative

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n.
a protein extract from cultures of tubercle bacilli, used to test whether a person has suffered from or been in contact with tuberculosis. In the Mantoux test a quantity of tuberculin is injected beneath the skin and a patch of inflammation appearing in the next 48-72 hours is regarded as a positive reaction, meaning that a degree of immunity is present.

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tu·ber·cu·lin (too-burґku-lin) [USP] a sterile solution containing growth products of Mycobacterium tuberculosis or M. bovis, used in skin tests for tuberculosis (see tuberculin test, under test) and also a commonly used antigen in laboratory immunology. It is provided as either Old tuberculin or purified protein derivative (PPD) tuberculin.

Medical dictionary. 2011.

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  • Tuberculin — is the name given to extracts of Mycobacterium tuberculosis, M. Bovis, or M. avium , used in skin testing in animals and humans to identify a tuberculosis infection [Tizard, I. R. (2004). Veterinary immunology: an introduction, seventh edition.… …   Wikipedia

  • Tuberculin — Tu*ber cu*lin, n. [See {Tubercle}.] A fluid containing the products formed by the growth of the tubercle bacillus in a suitable culture medium. [1913 Webster] …   The Collaborative International Dictionary of English

  • tuberculin — [too bʉr′kyə lin, təbʉr′kyə lin] n. [< L tuberculum (see TUBERCLE) + IN1] a sterile liquid preparation made from the growth products or extracts of a tubercle bacillus culture and injected into the skin as a test for tuberculosis …   English World dictionary

  • tuberculin — n. a sterile liquid from cultures of tubercle bacillus, used in the diagnosis and treatment of tuberculosis. Phrases and idioms: tuberculin test a hypodermic injection of tuberculin to detect a tubercular infection. tuberculin tested (of milk)… …   Useful english dictionary

  • tuberculin — n. a protein extract from cultures of tubercle bacilli, used to test whether a person has suffered from or been in contact with tuberculosis. In the Mantoux test a quantity of tuberculin is injected beneath the skin and a patch of inflammation… …   The new mediacal dictionary

  • tuberculin test — n a test (as the Mantoux test or tine test) for hypersensitivity to tuberculin in which tuberculin is introduced (as by injection or puncture) usu. into the skin of the individual tested and the appearance of inflammation or induration at the… …   Medical dictionary

  • Tuberculin test — Tu*ber cu*lin test The hypodermic injection of tuberculin, used as a test for past or present infection with tuberculosis. It is used both for humans and cattle. Note: In humans, a previous or acive infection with tuberculosis will cause a… …   The Collaborative International Dictionary of English

  • tuberculin reaction — n a skin reaction that occurs at the site of a tuberculin test <an induration measuring 10 mm or more is considered a positive tuberculin reaction for all individuals> * * * induration or vesiculation as a delayed reaction at the site of a… …   Medical dictionary

  • tuberculin test — noun a skin test to determine past or present infection with the tuberculosis bacterium; based on hypersensitivity of the skin to tuberculin • Syn: ↑tuberculin skin test • Hypernyms: ↑skin test • Hyponyms: ↑Mantoux test, ↑tine test * * * …   Useful english dictionary

  • tuberculin test — a test for tuberculosis in which a hypersensitive reaction to a given quantity of tuberculin indicates a past or present infection. [1900 05] * * * ▪ medicine       procedure for the diagnosis of tuberculosis infection by the introduction into… …   Universalium

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