tuberculin


tuberculin
1. A glycerin-broth culture of Mycobacterium tuberculosis evaporated to 110 volume at 100°C and filtered; introduced by Robert Koch for the treatment of tuberculosis but now used chiefly for diagnostic tests; originally known as Koch old t. (OT) or Koch original t. 2. One or another of a relatively large number of extracts of Mycobacterium tuberculosis cultures, different from OT and now obsolete.
- Koch old t. (OT) t. (1).
- purified protein derivative of t. (PPD) purified t. containing the active protein fraction; the t. from which it is prepared differs from t. (1) chiefly in that the bacteria are grown in a synthetic rather than in a broth medium.

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tu·ber·cu·lin t(y)u̇-'bər-kyə-lən n a sterile solution containing the growth products of or specific substances extracted from the tubercle bacillus and used in the diagnosis of tuberculosis see old tuberculin, purified protein derivative

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n.
a protein extract from cultures of tubercle bacilli, used to test whether a person has suffered from or been in contact with tuberculosis. In the Mantoux test a quantity of tuberculin is injected beneath the skin and a patch of inflammation appearing in the next 48-72 hours is regarded as a positive reaction, meaning that a degree of immunity is present.

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tu·ber·cu·lin (too-burґku-lin) [USP] a sterile solution containing growth products of Mycobacterium tuberculosis or M. bovis, used in skin tests for tuberculosis (see tuberculin test, under test) and also a commonly used antigen in laboratory immunology. It is provided as either Old tuberculin or purified protein derivative (PPD) tuberculin.

Medical dictionary. 2011.

Look at other dictionaries:

  • Tuberculin — is the name given to extracts of Mycobacterium tuberculosis, M. Bovis, or M. avium , used in skin testing in animals and humans to identify a tuberculosis infection [Tizard, I. R. (2004). Veterinary immunology: an introduction, seventh edition.… …   Wikipedia

  • Tuberculin — Tu*ber cu*lin, n. [See {Tubercle}.] A fluid containing the products formed by the growth of the tubercle bacillus in a suitable culture medium. [1913 Webster] …   The Collaborative International Dictionary of English

  • tuberculin — [too bʉr′kyə lin, təbʉr′kyə lin] n. [< L tuberculum (see TUBERCLE) + IN1] a sterile liquid preparation made from the growth products or extracts of a tubercle bacillus culture and injected into the skin as a test for tuberculosis …   English World dictionary

  • tuberculin — n. a sterile liquid from cultures of tubercle bacillus, used in the diagnosis and treatment of tuberculosis. Phrases and idioms: tuberculin test a hypodermic injection of tuberculin to detect a tubercular infection. tuberculin tested (of milk)… …   Useful english dictionary

  • tuberculin — n. a protein extract from cultures of tubercle bacilli, used to test whether a person has suffered from or been in contact with tuberculosis. In the Mantoux test a quantity of tuberculin is injected beneath the skin and a patch of inflammation… …   The new mediacal dictionary

  • tuberculin — noun Etymology: International Scientific Vocabulary Date: circa 1890 a sterile liquid containing the growth products of or specific substances extracted from the tubercle bacillus and used in the diagnosis of tuberculosis especially in children… …   New Collegiate Dictionary

  • tuberculin — /too berr kyeuh lin, tyoo /, n. Med. a sterile liquid prepared from cultures of the tubercle bacillus, used in the diagnosis and, formerly, in the treatment of tuberculosis. [1890 95; < L tubercul(um) TUBERCLE + IN2] * * * …   Universalium

  • tuberculin — noun An antigen used in the diagnosis of tuberculosis …   Wiktionary

  • tuberculin — n. (Medicine) sterile extract from cultures of the tubercle bacillus used in the diagnosis of the disease tuberculosis (and formerly in its treatment) …   English contemporary dictionary

  • tuberculin — [tjʊ bə:kjʊlɪn] noun a sterile protein extract from cultures of tubercle bacillus, used to test for tuberculosis. Origin C19: from L. tuberculum (see tubercle) + in1 …   English new terms dictionary


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