vinblastine sulfate


vinblastine sulfate
A dimeric alkaloid obtained from Vinca rosea. It arrests mitosis in metaphase (although vincristine is more active in this respect) and exhibits greater antimetabolic activity than does vincristine; used in the treatment of Hodgkin disease, choriocarcinoma, acute and chronic leukemias, and other neoplastic diseases; blocks microtubule assembly. SYN: vincaleucoblastine.

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vin·blas·tine sul·fate (vin-blasґtēn) [USP] the sulfate salt of a vinca alkaloid, used as an antineoplastic in treatment of lymphomas, including generalized Hodgkin disease, Kaposi sarcoma, advanced mycosis fungoides, Letterer-Siwe disease, choriocarcinoma resistant to other agents, breast carcinoma unresponsive to other therapy, and embryonal carcinoma of the testis. Administered intravenously.

Medical dictionary. 2011.

Look at other dictionaries:

  • vinblastine — [vin blas′tēn, vin blas′tin] n. an alkaloid, C46H58N4O9·H2SO4, obtained from the leaves of a periwinkle ( Vinca rosea) and used as a drug in the treatment of Hodgkin s disease and other lymphomas: in full vinblastine sulfate …   English World dictionary

  • Vinblastine — Général No CAS …   Wikipédia en Français

  • vinblastine — noun Etymology: contraction of vincaleukoblastine, from vinca + leukoblast developing leukocyte, from leuk + blast Date: 1962 an alkaloid C46H58N4O9 from the rosy periwinkle used especially in the form of its sulfate to treat human neoplastic… …   New Collegiate Dictionary

  • vinblastine — vin·blas·tine ( )vin blas .tēn n an alkaloid that is obtained from the rosy periwinkle and that is used esp. in the form of its sulfate C46H58N4O9·H2SO4 to treat human neoplastic diseases (as Hodgkin s disease and testicular carcinoma) called… …   Medical dictionary

  • vindesine sulfate — vin·de·sine sul·fate (vinґdə sēn) a synthetic vinca alkaloid derived from vinblastine sulfate, used as an antineoplastic in the treatment of acute lymphoblastic leukemia and non–small cell carcinoma; administered intravenously …   Medical dictionary

  • Hydrazine sulfate — IUPAC name Hydrazinium hydrogen sulfate …   Wikipedia

  • vincristine sulfate — A dimeric alkaloid obtained from Vinca rosea; its antineoplastic activity is similar to that of vinblastine, but no cross resistance develops between these two agents, and it is more useful than vinblastine in lymphocytic lymphosarcoma and acute… …   Medical dictionary

  • List of IARC Group 3 carcinogens — Substances, mixtures and exposure circumstances in this list have been classified by the IARC as Group 3: The agent (mixture or exposure circumstance) is not classifiable as to its carcinogenicity to humans. This category is used most commonly… …   Wikipedia

  • Vinblastin — Strukturformel Allgemeines Freiname Vinblastin Andere Namen …   Deutsch Wikipedia

  • vincaleucoblastine — SYN: vinblastine sulfate …   Medical dictionary


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