Monoclonal

Monoclonal
Pertaining to a single clone of cells, a single cell and the progeny of that cell. As opposed to polyclonal. A monoclonal tumor is one that is derived from a single cell and the progeny of that cell. Monoclonal antibodies are produced by a single clone of cells (hybridoma cells) and therefore are a single type of antibody.
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In immunochemistry, pertaining to a protein from a single clone of cells, all molecules of which are the same; e.g., in the case of Bence Jones protein, the chains are all κ or λ.

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mono·clo·nal .män-ə-'klōn-əl adj produced by, being, or composed of cells derived from a single cell <a \monoclonal tumor> esp relating to or being an antibody derived from a single cell in large quantities for use against a specific antigen (as a cancer cell)
monoclonal n a monoclonal antibody

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mono·clo·nal (mon″o-kloґnəl) derived from or pertaining to a single clone.

Medical dictionary. 2011.

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  • MONOCLONAL — Un produit issu d’un clone cellulaire a été synthétisé par une population de cellules absolument identiques, spécialement du point de vue de leur patrimoine génétique. Ce produit ne peut donc être constitué que de molécules identiquement codées,… …   Encyclopédie Universelle

  • Monoclonal — cells are defined as a group of cells produced from a single ancestral cell by repeated cellular replication. Thus they can be said to form a single clone .[1] The process of replication can occur in vivo, or may be stimulated in vitro for… …   Wikipedia

  • monoclonal — monoclonal. (De mono , clon2 y al). □ V. anticuerpo monoclonal …   Enciclopedia Universal

  • monoclonal — MONOCLONÁL, Ă adj. cu descendenţă pe cale asexuată din acelaşi strămoş. (< fr. monoclonal) Trimis de raduborza, 15.09.2007. Sursa: MDN …   Dicționar Român

  • monoclonal — (De mono , clon2 y al). ☛ V. anticuerpo monoclonal …   Diccionario de la lengua española

  • monoclonal — Relativo, perteneciente o que designa un grupo de células u organismos idénticos derivados de una única célula. Diccionario Mosby Medicina, Enfermería y Ciencias de la Salud, Ediciones Hancourt, S.A. 1999 …   Diccionario médico

  • monoclonal — [män΄ōklōn′əl, män΄əklōn′əl] adj. [ MONO + CLONAL] of cells derived or cloned from one cell …   English World dictionary

  • monoclonal — adjective Date: 1914 produced by, being, or composed of cells derived from a single cell < monoclonal antibodies > < a monoclonal tumor > • monoclonal noun …   New Collegiate Dictionary

  • monoclonal — /mon euh klohn l/, Biol. adj. 1. pertaining to cells or cell products derived from a single clone. n. 2. a monoclonal antibody or other monoclonal product. [1910 15; MONO + CLONE + AL1] * * * …   Universalium

  • monoclonal — mon•o•clo•nal [[t]ˌmɒn əˈkloʊn l[/t]] adj. 1) mcr lab pertaining to cells or cell products derived from a single biological clone 2) bai (mcr imv) a monoclonal antibody or other monoclonal product • Etymology: 1910–15 …   From formal English to slang

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