Phosphorylation


Phosphorylation
Phosphorylation is a biochemical process that involves the addition of phosphate to an organic compound. Phosphorylation may, for instance, involve the addition of phosphate to glucose to produce glucose monophosphate. Or phosphorylation may, for example, involve the addition of phosphate to ADP [adenosine diphosphate] to form ATP [adenosine triphosphate]. Phosphorylation is carried out through the action of enzymes known as phosphotransferases or kinases.
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Addition of phosphate to an organic compound, such as glucose to produce glucose monophosphate, through the action of a phosphotransferase (phosphorylase) or kinase.
- oxidative p. formation of high-energy phosphoric bonds ( e.g., in pyrophosphates) from the energy released by the flow of electrons to O2 and the dehydrogenation (i.e., oxidation) of various substrates, most notably isocitric acid, α-ketoglutaric acid, succinic acid, and malic acid in the tricarboxylic acid cycle.
- substrate-level p. the synthesis of ATP (or other NTP) not involving electron transport coupled with oxidative p. or with photophosphorylation.

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phos·phor·y·la·tion .fäs-.fȯr-ə-'lā-shən n the process of phosphorylating a chemical compound either by reaction with inorganic phosphate or by transfer of phosphate from another organic phosphate esp the enzymatic conversion of carbohydrates into their phosphoric esters in metabolic processes (as the conversion of glucose to glucose-6-phosphate by ATP and hexokinase)

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phos·phor·y·la·tion (fos-for″ə-laґshən) the metabolic process of introducing a phosphate group into an organic molecule. phosphorylated adj

Medical dictionary. 2011.

Look at other dictionaries:

  • Phosphorylation — is the addition of a phosphate (PO4) group to a protein molecule or a small molecule. It can also be thought of as the introduction of a phosphate group into an organic molecule . Its prominent role in biochemistry is the subject of a very large… …   Wikipedia

  • phosphorylation — [ fɔsfɔrilasjɔ̃ ] n. f. • 1938; de phosphoryle ♦ Biochim. Réaction chimique ou enzymatique au cours de laquelle un radical phosphate (PO3H2) se fixe sur un composé organique. ● phosphorylation nom féminin Mécanisme aboutissant à la fixation d une …   Encyclopédie Universelle

  • phosphorylation — phosphorylation. См. фосфорилирование. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Phosphorylation — chaîne latérale de sérine phosphorylée. Les atomes d oxygène sont en rouge, ceux de phosphore, en orange, le carbone en gris et l azote en bleu. Les atomes d hydrogène ne sont pas représentés. La phosphorylation est l addition d un groupe… …   Wikipédia en Français

  • phosphorylation — See phosphorylate. * * * ▪ chemical reaction       in chemistry, the addition of a phosphoryl group (PO32 ) to an organic compound. The process by which much of the energy in foods is conserved and made available to the cell is called oxidative… …   Universalium

  • phosphorylation — fosforilinimas statusas T sritis chemija apibrėžtis Fosfato rūgšties liekanos įjungimas į molekulę. atitikmenys: angl. phosphorylation rus. фосфорилирование …   Chemijos terminų aiškinamasis žodynas

  • phosphorylation — ˌ ̷ ̷ˌ ̷ ̷ ̷ ̷ˈlāshən noun ( s) Etymology: phosphoryl + ation : the process of phosphorylating either by reaction with inorganic phosphate or by transfer of phosphate from another organic phosphate; especially : the enzymatic conversion of… …   Useful english dictionary

  • phosphorylation — noun Date: 1925 the process of phosphorylating a chemical compound either by reaction with inorganic phosphate or by transfer of phosphate from another organic phosphate; especially the enzymatic conversion of carbohydrates into their phosphoric… …   New Collegiate Dictionary

  • phosphorylation — noun the process of transferring a phosphate group from a donor to an acceptor; often catalysed by enzymes …   Wiktionary

  • phosphorylation — n. addition of the phosphoryl group (Chemistry) …   English contemporary dictionary


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