- A turning back, repetition, duplication, reproduction.
* * *1. The execution of an experiment or study more than once so as to confirm the original findings, increase precision, and obtain a closer estimate of sampling error. 2. Autoreproduction or duplication, as in mitosis or cellular biology. See autoreproduction. 3. DNA-directed DNA synthesis. [L. replicatio, a reply, fr. replico, pp. -atus, to fold back]- bidirectional r. a situation in which DNA r. proceeds with two r. forks moving in opposite directions around a circle or D-loop-type structure.- conservative r. a hypothetical form of r. in which a double-stranded DNA (dsDNA) produces two daughter dsDNAs, one of which consists of the two original strands while the other daughter DNA consists of two newly synthesized chains.- semiconservative r. r. in which a double-stranded DNA (dsDNA) produces two daughter dsDNAs, each of which contains one of the original chains and one newly synthesized strand.
* * *rep·li·ca·tion .rep-lə-'kā-shən n1) the action or process of reproducing or duplicating <\replication of DNA>2) performance of an experiment or procedure more than once
* * *n.the process by which DNA makes copies of itself when the cell divides. The two strands of the DNA molecule unwind and each strand directs the synthesis of a new strand complementary to itself.
* * *rep·li·ca·tion (rep″lĭ-kaґshən) [L. replicatio a fold backwards] 1. a turning back of a part so as to form a duplication. 2. repetition of an experiment to ensure accuracy. 3. the process of duplicating or reproducing, as the replication of an exact copy of a strand of DNA or RNA.
Medical dictionary. 2011.