botulinum toxin


botulinum toxin
botulinum toxin also botulinus toxin n a very powerful bacterial neurotoxin that acts primarily on the parasympathetic nervous system, is produced by botulinum, blocks release of acetylcholine at the neuromuscular junction, and causes botulism often used with one of the letters A to G to designate one of seven distinct types called also botulin

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a powerful nerve toxin, produced by the bacterium Clostridium botulinum, that has proved effective, in minute dosage, for the treatment of various conditions of muscle overaction, such as strabismus (squint) and various dystonic conditions (see dystonia), including spasm of the orbicularis muscle in patients with blepharospasm; it is administered by injection. It is also used to treat achalasia, being injected through an endoscope into the gastro-oesophageal sphincter, and for relieving the spastic paralysis associated with cerebral palsy. Side-effects include prolonged local muscle paralysis. Trade names: Botox, Dysport.

Medical dictionary. 2011.

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  • Botulinum-Toxin — Botulinumtoxin Serotyp A (Clostridium botulinum) Bändermodell nach …   Deutsch Wikipedia

  • botulinum toxin — noun any of several neurotoxins that are produced by the anaerobic bacterium Clostridium botulinum; causes muscle paralysis • Hypernyms: ↑neurotoxin, ↑neurolysin • Hyponyms: ↑botulinum toxin A, ↑Botox …   Useful english dictionary

  • botulinum toxin A — noun a neurotoxin (trade name Botox) that is used clinically in small quantities to treat strabismus and facial spasms and other neurological disorders characterized by abnormal muscle contractions; is also used by cosmetic surgeons to smooth… …   Useful english dictionary

  • botulinum toxin — toxin that causes the potentially fatal disease botulism and is found in spoiled food (created by the bacteria Clostridium botulinum which is used in biological weapons and in very small doses to treat muscular disorders) …   English contemporary dictionary

  • botulinum toxin — Neurotoxin (50 kD; 7 distinct serotypes) produced by certain strains of Clostridium botulinum. The bacterium produces the toxin as a complex with a haemagglutinin that prevents toxin inactivation in the gut. Proteolysis in the body results in… …   Dictionary of molecular biology

  • botulinum toxin — noun Date: 1928 a neurotoxin formed by botulinum that causes botulism and that is injected in a purified form for therapeutic and cosmetic purposes (as to treat blepharospasm and reduce wrinkles) …   New Collegiate Dictionary

  • Botulinum toxin — noun a neurotoxic protein produced by the bacterium Clostridium botulinum Syn: botulin …   Wiktionary

  • botulinum toxin — [ˌbɒtjʊ lʌɪnəm] (also botulinus toxin) noun another term for botulin …   English new terms dictionary

  • botulinum toxin type A — n a purified botulinum toxin of high molecular weight that is used by injection esp. to treat strabismus, blepharospasm, spasmodic torticollis, and severe axillary hyperhidrosis and in cosmetic dermatology and plastic surgery to minimize wrinkles …   Medical dictionary