Cushing's syndrome

Cushing's syndrome
Cushing's syndrome n an abnormal bodily condition that is caused by excess corticosteroids and esp. cortisol usu. from adrenal or pituitary hyperfunction and that is characterized by a variety of signs and symptoms including esp. a change in appearance marked by moon facies with plethora, obesity, easy bruising, slow wound healing, and hypokalemia called also adrenogenital syndrome

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the condition resulting from excess amounts of corticosteroid hormones in the body. Symptoms include weight gain, reddening of the face and neck, excess growth of body and facial hair, raised blood pressure, loss of mineral from the bones (osteoporosis), raised blood glucose levels, and sometimes mental disturbances. The syndrome may be due to overstimulation of the adrenal glands by excessive amounts of the hormone ACTH, secreted either by a tumour of the pituitary gland (Cushing's disease) or by a malignant tumour in the lung or elsewhere. Other causes include a benign or malignant tumour of the adrenal gland(s) resulting in excess activity of the gland and prolonged therapy with high doses of corticosteroid drugs.
H. W. Cushing (1869-1939), US surgeon

Medical dictionary. 2011.

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Look at other dictionaries:

  • Cushing's syndrome — Classification and external resources ICD 10 E24 ICD 9 255.0 …   Wikipedia

  • Cushing's syndrome — Syndrome de Cushing Pour les articles homonymes, voir Cushing. Le syndrome de Cushing, ou hypercorticisme chronique, est une pathologie décrite par Harvey Cushing en 1932, qui se manifeste de manière clinique et est causée par un excès de… …   Wikipédia en Français

  • Cushing's syndrome — n. a medical condition characterized by obesity, hypertension, excessive hair growth, etc., caused by an overactive adrenal gland or large doses of corticosteroids * * * …   Universalium

  • Cushing's syndrome — n. a medical condition characterized by obesity, hypertension, excessive hair growth, etc., caused by an overactive adrenal gland or large doses of corticosteroids …   English World dictionary

  • Cushing's syndrome — the condition resulting from excess amounts of corticosteroid hormones in the body. Symptoms include weight gain, reddening of the face and neck, excess growth of body and facial hair, raised blood pressure, loss of mineral from the bones… …   The new mediacal dictionary

  • Cushing's syndrome — noun Medicine a metabolic disorder caused by overproduction of corticosteroid hormones by the adrenal cortex and often involving obesity and high blood pressure. Origin 1930s: named after the American surgeon Harvey W. Cushing …   English new terms dictionary

  • Cushing's syndrome — noun Date: 1937 an abnormal bodily condition that is caused by excess corticosteroids and especially cortisol usually from adrenal or pituitary hyperfunction and is characterized especially by obesity, hypertension, muscular weakness, and easy… …   New Collegiate Dictionary

  • Cushing's syndrome — A type of hypertensive disease in man due probably to the oversecretion of cortisol due in turn to excessive secretion of adrenocorticotrophic hormone (ACTH). Adrenal tumours are the usual primary cause …   Dictionary of molecular biology

  • Cushing's syndrome — noun Hyperadrenocorticism or hypercorticism, an endocrine disorder caused by high levels of cortisol in the blood …   Wiktionary

  • Cushing's syndrome — noun a glandular disorder caused by excessive cortisol • Syn: ↑hyperadrenocorticism • Hypernyms: ↑glandular disease, ↑gland disease, ↑glandular disorder, ↑adenosis …   Useful english dictionary

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