didanosine


didanosine
di·dan·o·sine dī-'dan-ə-.sēn n ddI

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n.
an antiviral drug that interferes with the action of the enzyme reverse transcriptase, by means of which HIV, the cause of AIDS, is able to incorporate itself into the human host cell. The drug is administered by mouth in attempts to prolong the lives of patients with HIV infection and AIDS. Possible side-effects include damage to nerves, severe pancreatitis, nausea, vomiting, and headache. Trade name: Videx.

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di·dan·o·sine (di-danґo-sēn) 2′3′-dideoxyinosine, a nucleoside analogue of 2′,3′-dideoxyadenosine; an antiretroviral agent that is converted intracellularly into the active metabolite dideoxyadenosine triphosphate, which inhibits viral replication both by incorporation into the viral genome and by interference with the action of reverse transcriptase; used for the treatment of advanced infection with human immunodeficiency virus-1 and acquired immunodeficiency syndrome; administered orally. Formerly called dideoxyinosine (ddI).

Medical dictionary. 2011.

Look at other dictionaries:

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  • didanosine — noun Etymology: alteration of dideoxyinosine, an alternate name, from di + deoxy + inosine, a nucleoside Date: 1990 ddI …   New Collegiate Dictionary

  • didanosine — di·dan·o·sine (dĭ dănʹə sēn , sĭn) n. See DDI.   [Shortening and alteration of dideoxyinosine.] * * * …   Universalium

  • didanosine — noun 2,3 dideoxyinosine, a reverse transcriptase inhibitor effective against HIV …   Wiktionary

  • didanosine — [dɪ danəʊsi:n] noun Medicine another term for dideoxyinosine …   English new terms dictionary

  • didanosine — di·dan·o·sine …   English syllables

  • didanosine — ddI; n. an antiretroviral drug that interferes with the action of the enzyme reverse transcriptase, by means of which HIV, the cause of AIDS, is able to incorporate itself into the human host cell. The drug is administered by mouth to prolong the …   The new mediacal dictionary

  • didanosine — A drug used in the treatment of infections caused by viruses …   English dictionary of cancer terms

  • didanosine — noun an antiviral drug used to combat HIV infection • Syn: ↑dideoxyinosine, ↑ddI, ↑DDI • Hypernyms: ↑antiviral, ↑antiviral agent, ↑antiviral drug …   Useful english dictionary