filgrastim


filgrastim
fil·gras·tim fil-'gras-təm n a genetically engineered human granulocyte colony-stimulating factor used to decrease the incidence of infection esp. as manifested by febrile neutropenia in patients affected with nonmyeloid malignant tumors see NEUPOGEN

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fil·gras·tim (fil-grasґtim) a human granulocyte colony-stimulating factor (G-CSF) produced by recombinant DNA technology, used to stimulate neutrophil production, reduce the duration of neutropenia, and reduce the incidence of infection in patients receiving myelosuppressive chemotherapy for nonmyeloid malignancies or following induction or consolidation chemotherapy for acute myelogenous leukemia, to accelerate recovery and promote engraftment after bone marrow transplantation, to enhance peripheral progenitor cell yield in autologous hematopoietic stem cell transplantation, and to treat chronic, severe neutropenia; administered subcutaneously or intravenously.

Medical dictionary. 2011.

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