gene conversion

gene conversion
gene conversion n a genetic process that is sometimes associated with meiotic recombination in heterozygotes if heteroduplex DNA is formed, that involves the selective enzymatic excision of a mismatched DNA sequence from one heteroduplex strand and replacement with a nucleotide sequence complementary to the other strand so that the two DNA strands are genetically identical, and that results in aberrant gametic ratios (as 3:1 or 1:3 instead of 2:2)

Medical dictionary. 2011.

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  • Gene conversion — is an event in DNA genetic recombination, which occurs at high frequencies during meiotic division but which also occurs in somatic cells. It is a process by which DNA sequence information is transferred from one DNA helix (which remains… …   Wikipedia

  • gene conversion — gene conversion. См. конверсия генов. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • gene conversion — noun Date: 1955 a genetic process that involves nonreciprocal meiotic recombination in heterozygotes in which a mismatched DNA sequence from one heteroduplex DNA strand is replaced with a sequence complementary to the other strand resulting in… …   New Collegiate Dictionary

  • gene conversion — A phenomenon in which alleles are segregated in a 3:1 not 2:2 ratio in meiosis. May be a result of DNA polymerase switching templates and copying from the other homologous sequence, or a result of mismatch repair (nucleotides being removed from… …   Dictionary of molecular biology

  • gene conversion —    The alteration of one strand of a heteroduplex DNA to make it complementary with the other strand at any position(s) where there were mispaired bases …   Forensic science glossary

  • gene conversion — A process, often associated with recombination, during which one allele is replicated at the expense of another, leading to non Mendelian segregation ratios …   Glossary of Biotechnology

  • gene conversion — noun : a genetic process that is sometimes associated with meiotic recombination in heterozygotes if heteroduplex DNA is formed, that involves the selective enzymatic excision of a mismatched DNA sequence from one heteroduplex strand and… …   Useful english dictionary

  • polar gene conversion — polar gene conversion. См. полярная генная конверсия. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Conversion génique biaisée — La conversion génique biaisée (ou BGC pour Biased Gene Conversion en anglais) est un biais de réparation de l ADN conduisant à l enrichissement des séquences en paires G C. Sommaire 1 Mécanisme de la conversion génique biaisée 2 Conséquences de… …   Wikipédia en Français

  • Gene duplication — Schematic of a region of a chromosome before and after a duplication event Gene duplication (or chromosomal duplication or gene amplification) is any duplication of a region of DNA that contains a gene; it may occur as an error in homologous… …   Wikipedia

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