Goodpasture's syndrome


Goodpasture's syndrome
Good·pas·ture's syndrome 'gu̇d-.pas-chərz- also Good·pas·ture syndrome -chər- n an autoimmune disorder of unknown cause that is characterized by the presence of circulating antibodies in the blood which attack the basement membrane of the kidney's glomeruli and the lung's alveoli and that is marked initially by coughing, fatigue, difficulty in breathing, and hemoptysis progressing to glomerulonephritis and pulmonary hemorrhages
Goodpasture Ernest William (1886-1960)
American pathologist. Goodpasture served for many years on the faculty of Vanderbilt University Medical School and as director of the research laboratory there. Known for his viral research, he was the first to study the progression of the herpes simplex virus along neural pathways to the central nervous system. In 1931 he demonstrated that fowl pox virus could be cultivated on the chorioallantoic membrane of the chick embryo and later showed that human viruses could be grown in the same way. He developed methods that made possible the commercial, mass production of vaccines against viral diseases such as smallpox, yellow fever, and influenza. Goodpasture described the syndrome that bears his name in 1919.

Medical dictionary. 2011.

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  • Goodpasture's syndrome — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 5363 ICD10 = ICD10|M|31|0|m|30 (ILDS M31.010) ICD9 = ICD9|446.21 ICDO = OMIM = 233450 MedlinePlus = eMedicineSubj = med eMedicineTopic = 923 eMedicine mult = eMedicine2|ped|888 MeshID =… …   Wikipedia

  • Goodpasture stain syndrome — Good·pas·ture stain, syndrome (goodґpas chər) [Ernest William Goodpasture, American pathologist, 1886–1960] see Stains and Staining Methods, under stain, and see under syndrome …   Medical dictionary

  • Goodpasture's syndrome — Disease in which there is accumulation of a very uniform layer of autoantibodies to components of basement membrane on the kidney glomerular basement membrane …   Dictionary of molecular biology

  • Syndrome de goodpasture — CIM 10: M31.0 {{{CIM10}}}.0 {{{X.0}}} …   Wikipédia en Français

  • Syndrome de Goodpasture — CIM 10 : M31.0 Le syndrome pneumo rénal de Goodpasture ou maladie des anticorps anti membrane basale glomérulaire est une maladie très rare d origine auto immune associant une hémorragie pulmonaire, une glomérulonéphrite extracapillaire, et… …   Wikipédia en Français

  • Syndrome nephritique — Syndrome néphritique Le syndrome néphritique (ou SNA) est une maladie des reins causée par l inflammation des glomérules, entraînant un passage des protéines et des globules rouges (hématies) du sang dans les urines, une poussée d hypertension… …   Wikipédia en Français

  • Goodpasture syndrome — An autoimmune disease characterized by a combination of lung and kidney disease specifically, pulmonary hemorrhage (bleeding in the lungs) and glomerulonephritis (inflammation of the glomerulus) due to severe inflammation in the basement… …   Medical dictionary

  • Syndrome néphritique — Le syndrome néphritique (ou SNA) est une maladie des reins causée par l inflammation des glomérules, entraînant un passage des protéines et des globules rouges (hématies) du sang dans les urines, une poussée d hypertension artérielle, et souvent… …   Wikipédia en Français

  • Syndrome, autoimmune polyendocrinopathy — A genetic autoimmune disease with an extraordinary array of clinical features but characterized most often by at least 2 of the following 3 findings: hypoparathyroidism underfunction of the parathyroid glands which control calcium, candidiasis… …   Medical dictionary

  • Goodpasture antibody — a type of circulating antibody against basement membrane antigens, present in Goodpasture syndrome …   Medical dictionary


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