- One of a group of drugs with antipsychotic activity which act by blocking postsynaptic (after-the-nerve) receptors for dopamine (a chemical that nerves use to communicate with one another) in the brain. Examples include: thiothixene (brand name: Navane), chlorprothixene (Remeron) and flupenthixol.
* * *A class of tricyclic compounds resembling phenothiazine, but with the central ring nitrogen replaced by a carbon atom; current use emphasizes the antipsychotic and antiemetic properties of this class.
* * *thio·xan·thene .thī-ō-'zan-.thēn n a compound C13H10S that is the parent compound of various antipsychotic drugs (as thiothixene) also a derivative of thioxanthene
* * *n.
* * *thio·xan·thene (thi″o-zanґthēn) 1. a three-ring compound structurally related to phenothiazine but having the nitrogen atom at position 10 replaced by a carbon atom with a double bond. 2. any of a class of structurally related antipsychotic agents derived from thioxanthene, including flupenthixol and thiothixene.
Medical dictionary. 2011.
Look at other dictionaries:
Thioxanthène — Général No CAS … Wikipédia en Français
Thioxanthene — is a molecule in which the oxygen atom in xanthene is replaced with a sulfur atom. Various thioxanthene derivatives are used in the treatment of schizophrenia and psychosis. The activity of these compounds is related to their ability to… … Wikipedia
thioxanthene — /thuy euh zan theen/, n. Pharm. any of a class of antipsychotics, as thiothixene, used to relieve symptoms of severe psychiatric disorders. [THIO + XANTH + ENE] * * * … Universalium
thioxanthene — noun The tricyclic heterocycle (sulfur analogue of xanthene) consisting of two benzene rings fused to that of thiopyran … Wiktionary
thioxanthene — n.; see antipsychotic … The new mediacal dictionary
thioxanthene — /thuy euh zan theen/, n. Pharm. any of a class of antipsychotics, as thiothixene, used to relieve symptoms of severe psychiatric disorders. [THIO + XANTH + ENE] … Useful english dictionary
Тиоксантен (Thioxanthene) — см. Средство антипсихотическое. Источник: Медицинский словарь … Медицинские термины
Thiothixene — Systematic (IUPAC) name (9Z) N,N dimethyl 9 [3 (4 methylpiperazin 1 yl)propylidene] 9H thioxanthene 2 sulfonamide Clinical data Trade names … Wikipedia
Chlorprothixene — Systematic (IUPAC) name (Z) 3 (2 chlorothioxanthen 9 ylidene) N, N dimethyl propan 1 amine Clinical data … Wikipedia
Clopenthixol — cis,trans mixture Systematic (IUPAC) name cis,trans 2 [4 [3 (2 chlorothioxanthen 9 ylidene) propyl]piperazin 1 yl]ethanol Clinical data … Wikipedia