histocompatibility antigen


histocompatibility antigen
histocompatibility antigen n any of the polymorphic glycoprotein molecules on the surface membranes of cells that aid in the ability of the immune system to determine self from nonself, that bind to and display antigenic peptide fragments for T cell recognition, and that are determined by the major histocompatibility complex

Medical dictionary. 2011.

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  • histocompatibility antigen — A set of plasmalemmal glycoproteins that are crucial for T cell recognition of antigens. Particularly the HLA system in humans and the H2 system in mice. There are two classes of histocompatibility antigens: (1) Class I; histocompatibility… …   Dictionary of molecular biology

  • histocompatibility antigen — noun : any of the antigenic glycoproteins on the surface membranes of cells that enable the body s immune system to recognize a cell as native or foreign and that are determined by the major histocompatibility complex * * * Immunol. any antigen… …   Useful english dictionary

  • histocompatibility antigen — noun any of the human leukocyte antigens (HLAs) which are the determinants of histocompatibility …   Wiktionary

  • histocompatibility antigen — Immunol. any antigen on the surface of tissue or blood cells that provokes the immune response and subsequent rejection when transplanted to an individual of a different antigenic type, thus determining whether the tissues or organs of a donor… …   Universalium

  • histocompatibility antigen — histocompatibil′ity an tigen n. imv any antigen on the surface of tissue or blood cells that provokes an immune response and subsequent rejection of the tissue or cell when transplanted to an individual of a different antigenic type • Etymology:… …   From formal English to slang

  • Minor histocompatibility antigen — are receptors on the cell surface of donated organs that are known to give an immunological response in some organ transplants[1]. They cause problems of rejection less frequently than those of the major histocompatibility complex (MHC). Minor… …   Wikipedia

  • major histocompatibility antigen — A set of plasmalemmal glycoprotein antigens involved in rapid (eg. 7 days in the mouse) graft rejection and other immune phenomena. The minor histocompatibility antigens are involved in much slower rejection phenomena. The major antigens show… …   Dictionary of molecular biology

  • major histocompatibility antigen — A cell surface protein or glycoprotein that allows the immune system to distinguish foreign or non self from self . A better term is histoglobulin. These are the antigens that must be matched between donors and recipients during organ and tissue… …   Glossary of Biotechnology

  • Antigen presentation — is a process in the body s immune system by which macrophages, dendritic cells and other cell types capture antigens and then enable their recognition by T cells. NOTOC The basis of adaptive immunity lies in the capacity of immune cells to… …   Wikipedia

  • Histocompatibility — is the property of having the same, or mostly the same, alleles of a set of genes called the major histocompatibility complex. These genes are expressed in most tissues as antigens, to which the immune system makes antibodies. The immune system… …   Wikipedia


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