hypervariable


hypervariable
hy·per·vari·able -'ver-ē-ə-bəl, -'var- adj relating to or being any of the relatively short polypeptide chain segments in the variable region of an antibody light chain or heavy chain that are extremely variable in the sequence of their amino acid residues and that determine the conformation and specificity of the site which recognizes and combines with an antigen also relating to, containing, or being a highly variable nucleotide sequence

Medical dictionary. 2011.

Look at other dictionaries:

  • Hypervariable — may refer to:*Hypervariable sequence, a segment of a chromosome characterised by considerable variation in the number of tandem repeats at one or more loci *Hypervariable locus, a locus with many alleles; especially those whose variation is due… …   Wikipedia

  • hypervariable — adjective Date: 1970 relating to or being any of the relatively short extremely variable polypeptide chain segments in the light chain or heavy chain of an antibody; also relating to, containing, or being a highly variable nucleotide sequence …   New Collegiate Dictionary

  • hypervariable — adj.; hypervariably, adv. * * * …   Universalium

  • hypervariable — adjective Containing a high degree of variability …   Wiktionary

  • hypervariable — hy·per·variable …   English syllables

  • hypervariable — hy per•var′i•a•ble adj …   From formal English to slang

  • hypervariable — ˌ adjective Etymology: hyper + variable (I) : relating to or being any of the relatively short polypeptide chain segments in the variable region of an antibody light chain or heavy chain that are extremely variable in the sequence of their amino… …   Useful english dictionary

  • hypervariable region — hypervariable region. См. гипервариабельный участок. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Hypervariable region — A hypervariable region (HVR) is a location within nuclear DNA or the D loop of mitochondrial DNA in which base pairs of nucleotides repeat (in the case of nuclear DNA) or have substitutions (in the case of mitochondrial DNA). Changes or repeats… …   Wikipedia

  • hypervariable region — Those regions of the heavy or light chains of immunoglobulins in which there is considerable sequence diversity within that set of immunoglobulins in a single individual. These regions specify the antigen affinity of each antibody …   Dictionary of molecular biology


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