low-density lipoprotein


low-density lipoprotein
low-den·si·ty lipoprotein 'lō-'den(t)-sət-ē- n LDL

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(LDL)

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(LDL) a class of lipoproteins responsible for transport of cholesterol to extrahepatic tissues. It is formed in the circulation when very-low-density lipoproteins are degraded first to intermediate-density lipoproteins and then to LDL by the gain and loss of specific apolipoproteins and the loss of most of their triglycerides. It is taken up and catabolized by both the liver and extrahepatic tissues by specific receptor-mediated endocytosis (see LDL receptors, under receptor). Called also (referring to its electrophoretic mobility) β-l.

Medical dictionary. 2011.

Look at other dictionaries:

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  • low-density lipoprotein — n. LDL …   English World dictionary

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  • low-density lipoprotein — LDL a lipoprotein that is the principal form in which cholesterol is transported in the bloodstream: it accounts for approximately 70% of the circulating cholesterol in an individual. LDL is derived from very low density lipoprotein and is… …   The new mediacal dictionary

  • low-density lipoprotein — low′ den sity lipopro′tein n. biochem. See LDL • Etymology: 1950–55 …   From formal English to slang

  • low-density lipoprotein — noun a lipoprotein that transports cholesterol in the blood; composed of moderate amount of protein and a large amount of cholesterol; high levels are thought to be associated with increased risk of coronary heart disease and atherosclerosis •… …   Useful english dictionary

  • low density lipoprotein — See lipoprotein …   Dictionary of molecular biology

  • low-density lipoprotein — noun a class of lipoprotein that transports cholesterol around the bloodstream; high levels may increase the risk of coronary heart disease …   Wiktionary