- Tuberous sclerosis
- A genetic disorder characterized by seizures, skin differences, benign tumors (tubers) that harden as the patient gets older, and developmental delays. Many children with tuberous sclerosis have autistic-like symptoms. Diagnosis is by observation of symptoms, particularly seizures combined with white spots on the skin that are most easily seen under ultraviolet light. Two genes associated with tuberous sclerosis have been found, one on chromosome 9, and one on chromosome 16, but genetic testing is not yet available. No treatment specifically for tuberous sclerosis is available, but surgery and medication can minimize associated problems.
* * *tuberous sclerosis n an inherited disorder of the skin and nervous system that is characterized typically by epilepsy and mental retardation, by a rash of the face resembling acne, and by multiple noncancerous tumors of the brain, kidney, retina, and heart and that is controlled by an autosomal dominant gene maintained in human populations by a high mutation rate called also epiloia
* * *a hereditary disorder in which the brain, skin, and other organs are studded with small plaques or tumours; eye involvement includes retinal tumours, optic nerve gliomas, and eyelid neuromas. Symptoms include epilepsy, mental retardation, and behavioural disorders.
* * *(TSC) see under complex.
Medical dictionary. 2011.