major histocompatibility complex

major histocompatibility complex
major histocompatibility complex n a group of genes in mammals that function esp. in determining the histocompatibility antigens found on cell surfaces and that in humans comprise the alleles occurring at four loci on the short arm of chromosome 6 abbr. MHC

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(MHC) the genes determining the major histocompatibility antigens, in all species a group of closely linked multiallelic genes located in a small region on one chromosome; designated the HLA c. in humans and the H-2 c. in mice.

Medical dictionary. 2011.

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