molecular distillation

molecular distillation
molecular distillation n distillation that is carried out under a high vacuum in an apparatus so designed as to permit molecules escaping from the warm liquid to reach the cooled surface of the condenser before colliding with other molecules and consequently returning to the liquid and that is used in the purification of substances of low volatility (as in the separation of vitamin A and vitamin E from fish-liver oils)

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a process of purification applied to drugs and pharmaceuticals during which the crude material is evaporated under high vacuum of about one millionth of an atmosphere, and the condensate is caught on a cooled surface held close in front of the evaporating layer. The process is applied currently to vitamins A, D, and E, to animal and vegetable sterols and hormones, and to drugs and intermediates.

Medical dictionary. 2011.

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