- muscular dystrophy
- muscular dystrophy n any of a group of hereditary diseases characterized by progressive wasting of muscles called also progressive muscular dystrophy see BECKER MUSCULAR DYSTROPHY, DUCHENNE MUSCULAR DYSTROPHY
* * *a group of muscle diseases, marked by weakness and wasting of selected muscles, in which there is a recognizable pattern of inheritance. The affected muscle fibres degenerate and are replaced by fatty tissue. The muscular dystrophies are classified according to the patient's age at onset, distribution of the weakness, the progression of the disease, and the mode of inheritance. Isolated cases may occur as a result of gene mutation. Confirmation of the diagnosis is based upon electromyography and muscle biopsy.One common form is Duchenne's muscular dystrophy, which is inherited as a sex-linked recessive character and is nearly always restricted to boys. It usually begins before the age of four, with selective weakness and wasting of the muscles of the pelvic girdle and back. The child has a waddling gait and lordosis of the lumbar spine. The calf muscles - and later the shoulders and upper limbs - often become firm and bulky. Although the disease cannot be cured, physiotherapy and orthopaedic measures can relieve the disability. The identification of the gene abnormality raises the possibility of gene therapy in the future. See also Becker muscular dystrophy, dystrophia myotonica.
* * *a group of genetic degenerative myopathies characterized by weakness and atrophy of muscle without involvement of the nervous system. The three main types are called pseudohypertrophic, facioscapulohumeral, and limb-girdle.
Medical dictionary. 2011.
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Muscular dystrophy — Classification and external resources ICD 10 G71.0 ICD 9 359.0 … Wikipedia
muscular dystrophy — noun uncount a serious illness in which your muscles gradually become weaker … Usage of the words and phrases in modern English
muscular dystrophy — ► NOUN ▪ a hereditary condition marked by progressive weakening and wasting of the muscles … English terms dictionary
muscular dystrophy — n. a chronic, noncontagious disease characterized by a progressive wasting of the muscles … English World dictionary
muscular dystrophy — Pathol. a hereditary disease characterized by gradual wasting of the muscles with replacement by scar tissue and fat, sometimes also affecting the heart. [1865 70] * * * Inherited disease that causes progressive weakness in the skeletal (and… … Universalium
muscular dystrophy — noun any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal muscles (Freq. 2) • Syn: ↑dystrophy • Hypernyms: ↑genetic disease, ↑genetic disorder, ↑genetic abnormality, ↑genetic defect … Useful english dictionary
muscular dystrophy — a group of muscle diseases, marked by weakness and wasting of selected muscles, in which there is a recognizable pattern of inheritance. The affected muscle fibres degenerate and are replaced by fatty tissue. The muscular dystrophies are… … The new mediacal dictionary
muscular dystrophy — noun Date: 1886 any of a group of hereditary diseases characterized by progressive wasting of muscles compare Becker muscular dystrophy, Duchenne muscular dystrophy … New Collegiate Dictionary
muscular dystrophy — [[t]mʌ̱skjʊlə(r) dɪ̱strəfi[/t]] N UNCOUNT Muscular dystrophy is a serious disease in which your muscles gradually weaken … English dictionary
muscular dystrophy — muscular dys|tro|phy [ˌmʌskjulə ˈdıstrəfi US lər ] n [U] a serious illness in which the muscles become weaker over a period of time … Dictionary of contemporary English