oxygen dissociation curve
- oxygen dissociation curve
oxygen dissociation curve -'kərv n a curve determined by plotting on a graph the partial pressure of oxygen in blood as the abscissa and the percentage of hemoglobin combined with oxygen in the form of oxyhemoglobin as the ordinate
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a graphic curve representing the normal variation in the amount of oxygen that combines with hemoglobin as a function of the partial pressure of oxygen. The curve is said to shift to the right (the Bohr effect) when less than a normal amount of oxygen is taken up by the blood at a given PO2, and to shift to the left (the Haldane effect) when more than a normal amount is taken up. Factors influencing the shape of the curve include changes in the blood pH, PCO2, and temperature, the presence of carbon monoxide, alterations in the constituents of the erythrocytes, and certain disease states. Called also oxygen-hemoglobin dissociation c.
Medical dictionary.
2011.
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