Wegener's granulomatosis

Wegener's granulomatosis
An uncommon type of inflammation of small arteries and veins (vasculitis) that classically involves the vessels supplying the tissues of the lungs, nasal passages (sinuses), and kidneys. Wegener's granulomatosis usually affects young or middle-aged adults. Symptoms include fatigue, weight loss, fever, shortness of breath, bloody sputum, joint pains, and sinus inflammation, sometimes with nasal ulcerations and bloody nasal discharge. The diagnosis of Wegener's granulomatosis is confirmed by finding evidence of vasculitis and abnormal cellular formations called granulomas on biopsy of tissue involved by the inflammatory process. Wegener's granulomatosis is a serious disease. Without treatment, it can be fatal within months. Treatment is directed toward stopping

* * *

Weg·e·ner's granulomatosis 'veg-ə-nərz- n an uncommon disease of unknown cause that is characterized esp. by vasculitis of small vessels, by granuloma formation in the respiratory tract, and by glomerulonephritis
Wegener Friedrich (1907-1990)
German pathologist. Wegener first described Wegener's granulomatosis in 1936, issuing another report in 1939. The disease was actually first described by German pathologist Heinz Karl Ernst Klinger in 1931.

* * *

an autoimmune disease predominantly affecting the nasal passages, lungs, and kidneys, characterized by granuloma formation in addition to arteritis. Untreated the disease is usually fatal, but it can be controlled (sometimes for years) with steroids, cyclophosphamide, and azathioprine.
F. Wegener (1907-90), German pathologist

Medical dictionary. 2011.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Wegener's granulomatosis — Classification and external resources Micrograph showing features characteristic of Wegener s granulomatosis a vasculitis and granulomas with multi nucleated giant cells …   Wikipedia

  • Wegener's granulomatosis — an autoimmune disease predominantly affecting the nasal passages, lungs, and kidneys, characterized by granuloma formation in addition to arteritis. Untreated the disease is usually fatal, but it can be controlled (sometimes for years) with… …   The new mediacal dictionary

  • Wegener&’s granulomatosis — A granulomatous vasculitis characterized by upper and lower respiratory tract granulomas and necrotising focal glomerulonephritis. Usually associated with autoantibodies to neutrophil cytoplasmic protease 3 (c ANCA) …   Dictionary of molecular biology

  • Granulomatosis de Wegener — Clasificación y recursos externos CIE 10 M31.3 CIE 9 446.4 MedlinePlus …   Wikipedia Español

  • Wegener — may refer to: * The disease Wegener s granulomatosis * Alfred Wegener, German geologist and meteorologist * Friedrich Wegener, a German pathologist * Gerda Wegener, Danish illustrator * Mike Wegener, Major League Baseball pitcher * Paul Wegener,… …   Wikipedia

  • Wegener-Granulomatose — Klassifikation nach ICD 10 M31.3 Wegener Granulomatose Nekrotisierende Granulomatose der Atemwege …   Deutsch Wikipedia

  • Granulomatosis, Wegener's — An inflammatory disease of small arteries and veins (vasculitis) that classically involves vessels supplying the tissues of the lungs, nasal passages (sinuses), and kidneys. Symptoms include fatigue, weight loss, fevers, shortness of breath,… …   Medical dictionary

  • granulomatosis — Any condition characterized by multiple granulomas. allergic g. SYN: Churg Strauss syndrome. lipid g., lipoid g. SYN: xanthomatosis. lymphomatoid g. angiocentric malignant lymphoma of the …   Medical dictionary

  • granulomatosis — n. any condition marked by multiple widespread granulomata. See also: Wegener s granulomatosis …   The new mediacal dictionary

  • granulomatosis de Wegener — f. reumat. Afección poco frecuente que empieza con una granulomatosis del tracto respiratorio y cuyos síntomas son sinusitis, ulceraciones de la mucosa nasal, otitis, tos y rinorrea. La supuración rinofaringea es necrosante y la mucosa nasal… …   Diccionario médico

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”