randomized controlled trial


randomized controlled trial
ran·dom·ized controlled trial 'ran-də-.mīzd- n a clinical trial in which the subjects are randomly distributed into groups which are either subjected to the experimental procedure (as use of a drug) or which serve as controls called also randomized clinical trial

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(RCT) a test in which subjects are assigned to groups in a random manner. In a clinical trial, an appropriate control group is used, such as to receive placebo or sham treatment or the standard well-established therapy, and this is compared with a group receiving experimental therapy; patients are assigned in a random manner to one of the groups, usually with blinding (see blind t.). This method is generally considered to yield the strongest scientific evidence of any well-designed trial.

Medical dictionary. 2011.

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