Xeroderma

Xeroderma
Abnormally dry skin. Xeroderma can be caused by a deficiency of vitamin A, systemic illness, overexposure to sunlight, or medication. It can usually be addressed by the use of over-the-counter (OTC) topical preparations. If these products do not relieve the condition, see an aesthetician or dermatologist for more specific remedies. From the Greek "xeros" meaning "dry" + the Greek "derma" meaning "skin" = dry skin.
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A mild form of ichthyosis characterized by excessive dryness of the skin due to slight increase of the horny layer and diminished water content of the stratum corneum from decreased perspiration, wind, or low humidity; seen with aging, atopic dermatitis, vitamin A deficiency, etc. [xero- + G. derma, skin]
- x. pigmentosum [MIM*278700] an eruption of exposed skin occurring in childhood and characterized by photosensitivity with severe sunburn in infancy and the development of numerous pigmented spots resembling freckles, larger atrophic lesions eventually resulting in glossy white thinning of the skin surrounded by telangiectases, and multiple solar keratoses that undergo malignant change at an early age; results from several rare autosomal recessive complementation groups in which DNA repair processes are defective, so that they are more liable to chromosome breaks and cancerous change when exposed to ultraviolet light. Severe ophthalmic and neurologic abnormalities are also found. SEE ALSO: De Sanctis-Cacchione syndrome.

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xe·ro·der·ma .zir-ə-'dər-mə n a disease of the skin characterized by dryness and roughness and a fine scaly desquamation

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n.
a mild form of the hereditary disorder ichthyosis, in which the skin develops slight dryness and forms branlike scales. It is common in the elderly. Xeroderma pigmentosum is a rare genetically determined disorder (see genodermatosis) in which there is an inherited defect in the mechanism that repairs damage to DNA brought about by ultraviolet radiation (see DNA repair); this leads to multiple skin cancers. Affected individuals must avoid any exposure to sunlight.

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xe·ro·der·ma (zēr″o-derґmə) [xero- + derma] a mild form of ichthyosis, marked by a dry, rough, discolored state of the skin, with the formation of a scaly desquamation.

Medical dictionary. 2011.

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Look at other dictionaries:

  • xeroderma — m. dermat. Afección cutánea que produce una piel seca, rugosa, descolorida y con tendencia a la descamación. Medical Dictionary. 2011. xeroderma …   Diccionario médico

  • Xeroderma — Xe ro*der ma, n. [NL., fr. Gr. ? dry + ? skin.] (Med.) (a) Ichthyosis. (b) A skin disease characterized by the presence of numerous small pigmented spots resembling freckles, with which are subsequently mingled spots of atrophied skin. [1913… …   The Collaborative International Dictionary of English

  • Xerodérma — (griech., »trockne Haut«; X. pigmentosum, Pergamenthaut, Dürrhaut), pergamentartiges Aussehen der Haut, das mit Verödung der Gefäße, Pigmentierung und Schwund der Oberhaut und des Fettpolsters einhergeht. X. ist eine seltene, stets in der… …   Meyers Großes Konversations-Lexikon

  • xeroderma — [zir΄ō dʉr′mə] n. [ XERO + DERMA1] ICHTHYOSIS …   English World dictionary

  • Xeroderma — The surface of the knuckles of a hand with xeroderma Xeroderma, literally meaning dry skin , is a condition involving the integumentary system, which in most cases can safely be treated with emollients and/or moisturizers. Xeroderma occurs most… …   Wikipedia

  • Xeroderma — Xe|ro|dẹr|ma 〈n.; s, dẹr|ma|ta od. dẹr|men; Med.〉 Xeroderma pigmentosum erblich bedingte, meist schon im Kindesalter tödlich verlaufende Hautkrankheit mit anfänglicher Flecken u. späterer Warzen u. Karzinombildung [zu grch. xeros „trocken“] *… …   Universal-Lexikon

  • Xeroderma — Græsk for tør hud. Xeroderma er desuden betegnelsen for en sjælden hudsygdom med tør og fast hud, fremkaldt af sollyset …   Danske encyklopædi

  • Xeroderma — Xe|ro|dẹr|ma 〈n.; Gen.: s, Pl.: ma|ta od. dẹr|men; Med.〉 Xeroderma pigmentosum erblich bedingte, meist schon im Kindesalter tödlich verlaufende Hautkrankheit mit anfänglicher Flecken u. späterer Warzen u. Karzinombildung [Etym.: <Xero… +… …   Lexikalische Deutsches Wörterbuch

  • xeroderma — n. a mild form of the hereditary disorder ichthyosis, in which the skin develops slight dryness and forms branlike scales. It is common in the elderly. Xeroderma pigmentosum is a rare genetically determined disorder (see genodermatosis) in which… …   The new mediacal dictionary

  • Xeroderma pigmentosum — Référence MIM Voir article Transmission Récessive Chromosome Voir article Gène Voir article Empreinte parentale Non Anticipation Non …   Wikipédia en Français

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