renal tubular acidosis

renal tubular acidosis
renal tubular acidosis n decreased ability of the kidneys to excrete hydrogen ions that is associated with a defect in the renal tubules without a defect in the glomeruli and that results in the production of urine deficient in acidity

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(RTA) a variety of metabolic acidosis resulting from impairment of renal function; it is usually accompanied by hyperchloremic acidosis, high urinary pH, bicarbonaturia, and lowered excretion of ammonium and titratable acids. Two types are distinguished according to whether the primary dysfunction is in distal or proximal tubules; see distal renal tubular a. and proximal renal tubular a.

Medical dictionary. 2011.

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