Rous sarcoma


Rous sarcoma
Rous sarcoma 'rau̇s- n a readily transplantable malignant fibrosarcoma of chickens that is caused by the Rous sarcoma virus
Rous Francis Peyton (1879-1970)
American pathologist. Rous spent almost all of his career as a researcher at the Rockefeller Institute of Medical Research. In a series of classic experiments involving hens he was able to transplant, by means of a cell-free filtrate, a sarcoma from one hen to another and to show that the cancer was of viral origin. He published an initial report of his findings in 1910. After further experimentation in 1911 in which he multiplied the number of transplanted tumors, he published in 1912 the first evidence that a virus was etiologically related to a malignant tumor. Because his findings contradicted prevailing medical opinion, his work was dismissed, and he had to wait decades before being vindicated. In 1915 and 1916 he studied the physiology of the blood and helped to develop a solution for preserving whole blood, an achievement which made possible the creation of the first blood banks. In the 1940s and 1950s he introduced new techniques that advanced the science of virology. In 1966 he was awarded the Nobel Prize for Physiology or Medicine.

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(rous) [Francis Peyton Rous, American pathologist and Nobel prize winner, 1879–1970] see under sarcoma.

Medical dictionary. 2011.

Look at other dictionaries:

  • rous sarcoma — noun also rous sarcoma or rous s sarcoma ˈrau̇s(ə̇z) Usage: usually capitalized R Etymology: after F. Peyton Rous b1879 American physician : a readily transplantable malignant spindle cell sarcoma of chickens that is transmissible by cell free… …   Useful english dictionary

  • Rous sarcoma — noun Etymology: F. Peyton Rous died 1970 American physician Date: circa 1911 a sarcoma of chickens caused by a retrovirus (species Rous sarcoma virus of the genus Alpharetrovirus) …   New Collegiate Dictionary

  • rous' sarcoma — noun see rous sarcoma …   Useful english dictionary

  • Rous sarcoma — Rous′ sarco ma [[t]raʊs[/t]] n. vet a malignant tumor occurring in the connective tissue of poultry, caused by a retrovirus • Etymology: after Francis PeytonRous(1879–1970), U.S. pathologist, who described it in 1910 …   From formal English to slang

  • Rous sarcoma — /rows/, Vet. Pathol. a malignant tumor occurring in the connective tissue of poultry, caused by a transmissible RNA containing virus. [after F. P. ROUS, who described it in 1910] * * * …   Universalium

  • Rous sarcoma — [raʊs] noun a form of tumour caused by an RNA virus, which affects birds, particularly poultry. Origin early 20th cent.: named after the American physician Francis P. Rous …   English new terms dictionary

  • Rous sarcoma virus — n a single stranded RNA virus of the family Retroviridae (species Rous sarcoma virus of the genus Alpharetrovirus) that contains an oncogene causing Rous sarcoma * * * (RSV) a usually defective virus of the genus Alpharetrovirus that produces… …   Medical dictionary

  • Rous sarcoma virus — Rous sarcoma virus. См. вирус саркомы Рaуса. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Rous sarcoma virus — Taxobox name = PAGENAME virus group = vi familia = Retroviridae subfamilia = Orthoretrovirinae genus = Alpharetrovirus species = Rous sarcoma virus Rous sarcoma virus is a retrovirus and is the first oncovirus to have been described: it causes… …   Wikipedia

  • Rous sarcoma virus (RSV) primer binding site (PBS) — This family represents a structured region around the Rous sarcoma virus primer binding site (PBS). This region is known to be required for the efficient initiation of reverse transcription. [cite journal | last = Johnson | first = M | coauthors …   Wikipedia


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