sulfonamide

sulfonamide
sul·fon·amide or chiefly Brit sul·phon·amide .səl-'fän-ə-.mīd, -məd; -'fō-nə-.mīd n any of various amides (as sulfanilamide) of a sulfonic acid also SULFA DRUG

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sul·fon·a·mide (səl-fonґə-mīd) 1. an organic compound containing the SO2NH2 group. 2. any of a class of drugs, the sulfa drugs, which are derivatives of sulfanilamide, competitively inhibiting folic acid synthesis in microorganisms and formerly bacteriostatic against gram-positive cocci (streptococci and pneumococci), gram-negative cocci (meningococci and gonococci), gram-negative bacilli (Escherichia coli and shigellae), a wide variety of other bacteria, and some protozoa. Because many strains of bacteria have developed resistance to sulfonamides, particularly to agents used singly, they have largely been supplanted by more effective and less toxic antibiotics, and when used are generally combined with another sulfonamide or other antimicrobial agent.

Medical dictionary. 2011.

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  • Sulfonamide — may refer to:* Sulfonamide (chemistry) the sulfonamide functional group (organic chemistry) * Sulfonamide (medicine) the group of sulfonamide antibacterial drugs …   Wikipedia

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  • sulfonamide — sulfamidas statusas T sritis chemija formulė RSO₂NH₂ atitikmenys: angl. sulfamide; sulfonamide rus. сульфамид …   Chemijos terminų aiškinamasis žodynas

  • Sulfonamide (medicine) — There are several sulfonamide based groups of drugs. The original antibacterial sulfonamides (sometimes called simply sulfa drugs) are synthetic antimicrobial agents that contain the sulfonamide group. Some sulfonamides are also devoid of… …   Wikipedia

  • Sulfonamide (chemistry) — In chemistry, the sulfonamide functional group (also spelt sulphonamide ) is S(=O)2 NH2, a sulfonyl group connected to an amine group.A sulfonamide (compound) is a compound that contains this group. The general formula is RSO2NH2, where R is some …   Wikipedia

  • sulfonamide — noun Etymology: sulfonic + amide Date: 1881 any of various amides (as sulfanilamide) of a sulfonic acid; also sulfa drug …   New Collegiate Dictionary

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